SNOG

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Cat.No. 0603 - SNOG | C10H16N4O7S | CAS No. 57564-91-7
Description: NO carrier. Breaks down to release NO
Chemical Name: S-Nitrosoglutathione
Datasheet
Citations
Literature

Biological Activity

A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.

Technical Data

M. Wt 336.32
Formula C10H16N4O7S
Storage Desiccate at -20°C
CAS Number 57564-91-7
PubChem ID 104858
InChI Key HYHSBSXUHZOYLX-WDSKDSINSA-N
Smiles N[C@@H](CCC(N[C@@H](CSN=O)C(NCC(O)=O)=O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 336.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.97 mL 14.87 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL
10 mM 0.3 mL 1.49 mL 2.97 mL
50 mM 0.06 mL 0.3 mL 0.59 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Bannenberg et al (1995) Characterization of the bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung. J.Pharmacol.Exp.Ther. 272 1238 PMID: 7891339

Gibson et al (1992) An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus. Br.J.Pharmacol. 107 715 PMID: 1472969

Radomski et al (1992) S-Nitroso-glutathione inhibits platelet activation in vitro and in vivo. Br.J.Pharmacol. 107 745 PMID: 1335336


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Keywords: SNOG, supplier, NO, carrier, Breaks, down, release, ROS, Donors, Precursors, Nitric, Oxide, Signaling, Signalling, NO, Donors, /, Precursors, ROS, Donors, NO, Donors, /, Precursors, Tocris Bioscience

Citations for SNOG

Citations are publications that use Tocris products.

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