SGC AAK1 1N

Pricing Availability   Qty
Cat.No. 6529 - SGC AAK1 1N | C20H22N4O3S | CAS No. 2242913-80-8
Description: Negative control for SGC AAK1 1 (Cat.No. 6528)
Chemical Name: N-[6-[3-[(Cyclopropylsulfonyl)amino]phenyl]-1H-indazol-3-yl]-2-methylpropanamide
Purity: ≥97% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for SGC AAK1 1N

SGC AAK1 1N is a negative control for SGC AAK1 1 (Cat. No. 6528).

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC-AAK1-1 probe summary on the SGC website.

Technical Data for SGC AAK1 1N

M. Wt 398.48
Formula C20H22N4O3S
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 2242913-80-8
PubChem ID 146121078
InChI Key RAIAORGFMNXPOV-UHFFFAOYSA-N
Smiles O=C(C(C)C)NC1=NNC2=C1C=CC(C3=CC=CC(NS(=O)(C4CC4)=O)=C3)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for SGC AAK1 1N

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.85 100
ethanol 3.98 10

Preparing Stock Solutions for SGC AAK1 1N

The following data is based on the product molecular weight 398.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.51 mL 12.55 mL 25.1 mL
5 mM 0.5 mL 2.51 mL 5.02 mL
10 mM 0.25 mL 1.25 mL 2.51 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References for SGC AAK1 1N

References are publications that support the biological activity of the product.

Agajanian (2019) WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop. Cell Rep. 26 79 PMID: 30605688


If you know of a relevant reference for SGC AAK1 1N, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Other Kinase Controls

Keywords: SGC AAK1 1N, SGC AAK1 1N supplier, SGCAAK11N, negative, control, for, SGC, AAK1, 1, inhibitor, inhibits, BMP2K, Other, Kinases, 6529, Tocris Bioscience

Citations for SGC AAK1 1N

Citations are publications that use Tocris products.

Currently there are no citations for SGC AAK1 1N. Do you know of a great paper that uses SGC AAK1 1N from Tocris? Please let us know.

Reviews for SGC AAK1 1N

There are currently no reviews for this product. Be the first to review SGC AAK1 1N and earn rewards!

Have you used SGC AAK1 1N?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Kinases Product Listing

Kinases Product Listing

A collection of over 400 products for kinase research, the listing includes inhibitors of:

  • Receptor Tyrosine Kinases
  • Protein Kinases A, C, D and G
  • PI-3 Kinase, Akt and mTOR
  • MAPK Signaling
  • Receptor Serine/Threonine Kinases