SCOTfluor glucose probe 510

Pricing Availability   Qty
Description: Fluorescent glucose probe
Chemical Name: 2-Deoxy-2-[(7-nitro-2,1,3-benzoselenadiazol-4-yl)amino]-D-glucose
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity for SCOTfluor glucose probe 510

SCOTfluor glucose probe 510 is a fluorescent probe for visualizing glucose uptake in vivo. It can be multiplexed with BFP and GFP. Excitation and emission maxima (λ) are 490 and 605 nm, respectively.

Licensing Information

Sold under license from the University of Edinburgh

Optical Data for SCOTfluor glucose probe 510

Emission Color Red
λabs 490 nm
λem 605 nm
Closest Laser line 488 nm
Cell Permeable Yes
Application Fluorescence microscopy

Technical Data for SCOTfluor glucose probe 510

M. Wt 405.23
Formula C12H14N4O7Se
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2490298-72-9
PubChem ID 155694629
Smiles OC[C@H]1OC([C@@H]([C@H]([C@@H]1O)O)NC2=CC=C(N(=O)=O)C3=N[Se]N=C23)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for SCOTfluor glucose probe 510

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 4.05 10

Preparing Stock Solutions for SCOTfluor glucose probe 510

The following data is based on the product molecular weight 405.23. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.68 mL 123.39 mL 246.77 mL
0.5 mM 4.94 mL 24.68 mL 49.35 mL
1 mM 2.47 mL 12.34 mL 24.68 mL
5 mM 0.49 mL 2.47 mL 4.94 mL

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Product Datasheets for SCOTfluor glucose probe 510

References for SCOTfluor glucose probe 510

References are publications that support the biological activity of the product.

Benson et al (2019) SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism. Angew.Chem.Int.Ed.Engl. 58 6911 PMID: 30924239

Benson et al (2021) Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo. Nat.Commun. 12 2369 PMID: 33888691

If you know of a relevant reference for SCOTfluor glucose probe 510, please let us know.

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Citations for SCOTfluor glucose probe 510

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