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SenTraGor™ is a reagent for detecting lipofuscin in senescent cells. A highly lipophilic and biotinylated analog of Sudan Black B; can be detected using an anti-biotin antibody. Can be used in vivo and in vitro in any biological material including cell cultures, fresh and frozen tissues, and fixed embedded samples. Compatible with immunohistochemistry, flow cytometry and immunofluorescence analysis.
Sold under license from University of Manchester Innovation Factory
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|ethanol||6.99||10 with gentle warming|
The following data is based on the product molecular weight 698.85. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||7.15 mL||35.77 mL||71.55 mL|
|1 mM||1.43 mL||7.15 mL||14.31 mL|
|2 mM||0.72 mL||3.58 mL||7.15 mL|
|10 mM||0.14 mL||0.72 mL||1.43 mL|
References are publications that support the biological activity of the product.
Evangelou et al (2017) Robust, universal biomarker assay to detect senescent cells in biological specimens Aging Cell 16 192 PMID: 28165661
If you know of a relevant reference for SenTraGor™, please let us know.
Keywords: SenTraGor™, SenTraGor™ supplier, sudan, black, B, lipofuscin, biotin, biotinylated, senescent, senescence, detection, detector, biomarker, GL13, Labels, and, Stains, 7555, Tocris Bioscience
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This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our: