Pricing Availability   Qty
Description: PAR2 receptor agonist
Purity: ≥95% (HPLC)
Citations (1)

Biological Activity for SLIGKV-NH2

SLIGKV-NH2 is a protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.

Control Peptide also available.

Technical Data for SLIGKV-NH2

M. Wt 614.78
Formula C28H54N8O7
Sequence SLIGKV

(Modifications: Val-6 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 190383-13-2
PubChem ID 10483914
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for SLIGKV-NH2

Solubility Soluble to 1 mg/ml in water

Product Datasheets for SLIGKV-NH2

Certificate of Analysis / Product Datasheet
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References for SLIGKV-NH2

References are publications that support the biological activity of the product.

Bohm et al (1996) Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem.J. 314 1009 PMID: 8615752

Hollenberg and Compton (2002) International union of pharmacology XXVIII. Proteinase-activated receptors. Pharmacol.Rev. 54 203 PMID: 12037136

Kanke et al (2005) Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2. Br.J.Pharmacol. 145 255 PMID: 15765104

If you know of a relevant reference for SLIGKV-NH2, please let us know.

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Keywords: SLIGKV-NH2, SLIGKV-NH2 supplier, PAR2, receptor, agonists, Receptors, Protease-Activated, proteinase-activated, 3010, Tocris Bioscience

1 Citation for SLIGKV-NH2

Citations are publications that use Tocris products. Selected citations for SLIGKV-NH2 include:

Namkung et al (2016) Monitoring G protein-coupled receptor and [beta]-arrestin trafficking in live cells using enhanced bystander BRET Nature Communications 7 12178 PMID: 27397672

Do you know of a great paper that uses SLIGKV-NH2 from Tocris? Please let us know.

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