Standard D2-like dopamine receptor antagonist.S-enantiomer also available.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|1eq. HCl||17.07||50mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 341.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.93 mL||14.64 mL||29.29 mL|
|5 mM||0.59 mL||2.93 mL||5.86 mL|
|10 mM||0.29 mL||1.46 mL||2.93 mL|
|50 mM||0.06 mL||0.29 mL||0.59 mL|
References are publications that support the products' biological activity.
Seeman and Van Tol (1993) Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. Eur.J.Pharmacol. 233 173 PMID: 8097160
Seeman and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15 264 PMID: 7940991
If you know of a relevant reference for (RS)-(±)-Sulpiride, please let us know.
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Keywords: (RS)-(±)-Sulpiride, supplier, selective, D2-like, antagonists, Dopamine, Non-Selective, Receptors, dopaminergic, Non-selective, Dopamine, Non-selective, Dopamine, Tocris Bioscience
3 Citations for (RS)-(±)-Sulpiride
Citations are publications that use Tocris products. Selected citations for (RS)-(±)-Sulpiride include:
Holroyd et al (2015) Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues. Brain 40 1495 PMID: 25547712
Zhang et al (2013) Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians. Physiol Behav 112-113 8 PMID: 23415661
Shin et al (2011) Exposure to extremely low frequency magnetic fields induces fos-related antigen-immunoreactivity via activation of dopaminergic d1 receptor. Neuropsychopharmacology 20 130 PMID: 22110371
Do you know of a great paper that uses (RS)-(±)-Sulpiride from Tocris? If so please let us know.
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