Somatostatin 1-28

Pricing Availability Delivery Time Qty
Cat.No. 1165 - Somatostatin 1-28 | Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: 17 - 28) | CAS No. 74315-46-1
Description: sst receptor agonist
Datasheet
Citations
Literature

Biological Activity

Somatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin.

Technical Data

M. Wt 3149
Formula C137H207N41O39S3
Sequence SANSNPAMAPRERKAGCKNFFWKTFTSC

(Modifications: Disulfide bridge between 17 - 28)

Storage Desiccate at -20°C
CAS Number 74315-46-1
PubChem ID 16133849
InChI Key GGYTXJNZMFRSLX-DFTNLTQTSA-N
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3149. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.32 mL 1.59 mL 3.18 mL
5 mM 0.06 mL 0.32 mL 0.64 mL
10 mM 0.03 mL 0.16 mL 0.32 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Panetta et al (1994) Molecular cloning, functional characterization and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28. Mol.Pharmacol. 45 417 PMID: 7908405

Patel et al (1994) Expression of multiple somatostatin receptor genes in AtT-20 cells. Evidence for a novel somatostatin-28 selective receptor subtype. J.Biol.Chem. 269 1506 PMID: 7904601

Shimokawa et al (1997) Effect of somatostatin-28 on growth hormone response to growth hormone-releasing hormone-impact of aging and lifelong dietary restriction. Neuroendocrinol. 65 369 PMID: 9158069


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Keywords: Somatostatin receptor agonist sst Receptors Somatostatin1-28 Somatostatin Receptors

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