Potent MCT1 inhibitor (IC50 = 0.5 nM); blocks proliferation of Raji lymphoma cells in vitro. Also inhibits lactate uptake in breast cancer cells in vitro.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 435.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.3 mL||11.48 mL||22.96 mL|
|5 mM||0.46 mL||2.3 mL||4.59 mL|
|10 mM||0.23 mL||1.15 mL||2.3 mL|
|50 mM||0.05 mL||0.23 mL||0.46 mL|
References are publications that support the products' biological activity.
Murray et al (2005) Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat.Chem.Biol. 1 371 PMID: 16370372
Wang et al (2014) Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. J.Med.Chem. 57 7317 PMID: 25068893
If you know of a relevant reference for SR 13800, please let us know.
View Related Products by Product Action
Keywords: SR 13800, supplier, SR13800, potent, MCT1, inhibitors, inhibits, lactate, uptake, anticancer, antitumour, antitumor, SLC16A1, monocarboxylate, transporters, Monocarboxylate, Transporters, Monocarboxylate, Transporters, Tocris Bioscience
Citations for SR 13800
Citations are publications that use Tocris products.
Currently there are no citations for SR 13800. Do you know of a great paper that uses SR 13800 from Tocris? If so please let us know.
Reviews for SR 13800
There are currently no reviews for this product. Be the first to review SR 13800 and earn rewards!
Have you used SR 13800?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.