SUN-B 8155

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Cat.No. 2550 - SUN-B 8155 | C14H15N3O3 | CAS No. 345893-91-6
Description: Non-peptide calcitonin (CT) receptor agonist
Chemical Name: 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone
Datasheet
Citations
Literature

Biological Activity

Non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC50 = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.

Compound Libraries

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Technical Data

M. Wt 273.29
Formula C14H15N3O3
Storage Store at +4°C
CAS Number 345893-91-6
PubChem ID 16079007
InChI Key IMUCOECFKIWBSW-LCYFTJDESA-N
Smiles O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.32 100

Preparing Stock Solutions

The following data is based on the product molecular weight 273.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.66 mL 18.3 mL 36.59 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
10 mM 0.37 mL 1.83 mL 3.66 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Katayama et al (2001) Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin. Biochim.Biophys.Acta 1526 183 PMID: 11325540


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Keywords: SUN-B 8155, supplier, Non-peptide, calcitonin, CT, receptors, agonists, SUNB8155, Calcitonin, and, Related, Receptors, Calcitonin, and, Related, Receptors, Tocris Bioscience

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