SUN-B 8155

Pricing Availability   Qty
Description: Non-peptide calcitonin agonist
Chemical Name: 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone
Literature (1)

Biological Activity for SUN-B 8155

SUN-B 8155 is a non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC50 = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.

Compound Libraries for SUN-B 8155

SUN-B 8155 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for SUN-B 8155

M. Wt 273.29
Formula C14H15N3O3
Storage Store at +4°C
CAS Number 345893-91-6
PubChem ID 16079007
Smiles O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for SUN-B 8155

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 27.32 100

Preparing Stock Solutions for SUN-B 8155

The following data is based on the product molecular weight 273.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.66 mL 18.3 mL 36.59 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
10 mM 0.37 mL 1.83 mL 3.66 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

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Product Datasheets for SUN-B 8155

Certificate of Analysis / Product Datasheet
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References for SUN-B 8155

References are publications that support the biological activity of the product.

Katayama et al (2001) Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin. Biochim.Biophys.Acta 1526 183 PMID: 11325540

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Keywords: SUN-B 8155, SUN-B 8155 supplier, Non-peptide, calcitonin, CT, receptors, agonists, SUNB8155, Calcitonin, and, Related, Receptors, 2550, Tocris Bioscience

Citations for SUN-B 8155

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Literature in this Area

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Peptides Involved in Appetite Modulation Scientific Review

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.