Somatostatin

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Cat.No. 1157 - Somatostatin | Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: 3 - 14) | CAS No. 51110-01-1
Description: Influences growth hormone release
Datasheet
Citations (2)
Reviews
Literature (3)

Biological Activity

Endogenous peptide; inhibits the release of growth hormone, insulin and glucagon. Inhibits voltage-dependent calcium channels.

Technical Data

M. Wt 1637.88
Formula C76H104N18O19S2
Sequence AGCKNFFWKTFTSC

(Modifications: Disulfide bridge between 3 - 14)

Storage Desiccate at -20°C
CAS Number 51110-01-1
PubChem ID 16129706
InChI Key NHXLMOGPVYXJNR-ATOGVRKGSA-N
Smiles [H]N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.30 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Alderton et al (1998) Differential effects of somatostatin and angiopeptin on cell proliferation. Br.J.Pharmacol. 124 323 PMID: 9641549

Dileepan et al (1985) Somatostatin: a metabolic regulator. Life Sci. 37 2335 PMID: 2867445

Ohmura et al (1990) Somatostatin decreases the calcium inward current in guinea-pig atria. Br.J.Pharmacol. 99 587 PMID: 1970502


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View all Somatostatin (sst) Receptor Agonists

Keywords: Somatostatin, Somatostatin supplier, Influences, growth, hormone, release, sst, Receptors, Somatostatin, 1157, Tocris Bioscience

2 Citations for Somatostatin

Citations are publications that use Tocris products. Selected citations for Somatostatin include:

Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888

Chiu et al (2013) Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501 52 PMID: 23965627


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Literature in this Area

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