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Secretin (rat)

Cat. No. 1919 Datasheet / COA / SDS
Pricing Availability Delivery Time Qty
Cat.No. 1919 - Secretin (rat) | His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Gln-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 | CAS No. 121028-49-7
Description: Gastrointestinal peptide
Datasheet
Citations
Reviews
Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Gastrointestinal peptide that stimulates pancreatic and biliary secretion. Also thought to play a role in the regulation of the hypothalamus-pituitary-adrenal axis.

Secretin (human) also available.

Technical Data

M. Wt 3027.38
Formula C129H216N42O42
Sequence HSDGTFTSELSRLQDSARLQRLLQGLV

(Modifications: Val-27 = C-terminal amide)
Storage Desiccate at -20°C
CAS Number 121028-49-7
PubChem ID 90488725
InChI Key LKHWQEXKRMDFFJ-NEMWHCQRSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3027.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.33 mL 1.65 mL 3.3 mL
5 mM 0.07 mL 0.33 mL 0.66 mL
10 mM 0.03 mL 0.17 mL 0.33 mL
50 mM 0.01 mL 0.03 mL 0.07 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Ng et al (2002) Secretin as a neuropeptide. Mol.Neurobiol. 26 97 PMID: 12392059

Nussdorfer et al (2000) Secretin, glucagon, gastric inhibitor polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus-pituitary-adrenal axis. Peptides 21 309 PMID: 10764961

Sherwood et al (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/Glucagon superfamily. Endocrine Rev. 21 619 PMID: 11133067

If you know of a relevant reference for Secretin (rat), please let us know.

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Keywords: Secretin (rat), supplier, Gastrointestinal, peptide, Secretin, Receptors, Glucagon, Secretin, Receptors, Secretin, Receptors, Tocris Bioscience

Citations for Secretin (rat)

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