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Secretin (rat)

Cat. No. 1919 Submit a Review Datasheet / COA / SDS
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Cat.No. 1919 - Secretin (rat) | His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Gln-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 | CAS No. 121028-49-7
Description: Gastrointestinal peptide
Datasheet
Citations
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Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Gastrointestinal peptide that stimulates pancreatic and biliary secretion. Also thought to play a role in the regulation of the hypothalamus-pituitary-adrenal axis.

Secretin (human) also available.

Technical Data

M. Wt 3027.38
Formula C129H216N42O42
Sequence HSDGTFTSELSRLQDSARLQRLLQGLV

(Modifications: Val-27 = C-terminal amide)
Storage Desiccate at -20°C
CAS Number 121028-49-7
PubChem ID 90488725
InChI Key LKHWQEXKRMDFFJ-NEMWHCQRSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 2 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the biological activity of the product.

Ng et al (2002) Secr. as a neuropeptide. Mol.Neurobiol. 26 97 PMID: 12392059

Nussdorfer et al (2000) Secr., glucagon, gastric inhibitor polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus-pituitary-adrenal axis. Peptides 21 309 PMID: 10764961

Sherwood et al (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/Glucagon superfamily. Endocrine Rev. 21 619 PMID: 11133067

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Keywords: Secretin (rat), Secretin (rat) supplier, Gastrointestinal, peptide, Secretin, Receptors, Glucagon, 1919, Tocris Bioscience

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Literature in this Area

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