You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
SSR 180711 hydrochloride
Biological Activity for SSR 180711 hydrochloride
SSR 180711 hydrochloride is a partial agonist at α7 nAChR. Enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. Increases extracellular dopamine levels in rat prefrontal cortex. Also exhibits antidepressant-like properties.
Technical Data for SSR 180711 hydrochloride
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SSR 180711 hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for SSR 180711 hydrochloride
The following data is based on the product molecular weight 361.66. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.77 mL||13.83 mL||27.65 mL|
|5 mM||0.55 mL||2.77 mL||5.53 mL|
|10 mM||0.28 mL||1.38 mL||2.77 mL|
|50 mM||0.06 mL||0.28 mL||0.55 mL|
Product Datasheets for SSR 180711 hydrochloride
References for SSR 180711 hydrochloride
References are publications that support the biological activity of the product.
Jones et al (2014) Effect of α7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats. Psychopharmacology (Berl). 231 673 PMID: 24057763
Pichat et al (2007) SSR180711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia. Neuropsychopharmacology 32 17 PMID: 16936709
If you know of a relevant reference for SSR 180711 hydrochloride, please let us know.
View Related Products by Product Action
Keywords: SSR 180711 hydrochloride, SSR 180711 hydrochloride supplier, SSR180711, hydrochloride, partial, agonists, a7, nAChR, nicotine, acetylcholine, receptor, schizophrenia, episodic, memory, antidepressant, Nicotinic, (a7), Receptors, 5559, Tocris Bioscience
Citations for SSR 180711 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for SSR 180711 hydrochloride. Do you know of a great paper that uses SSR 180711 hydrochloride from Tocris? Please let us know.
Reviews for SSR 180711 hydrochloride
There are currently no reviews for this product. Be the first to review SSR 180711 hydrochloride and earn rewards!
Have you used SSR 180711 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.