You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Inhibitor of α-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 173.21. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||11.55 mL||57.73 mL||115.47 mL|
|2.5 mM||2.31 mL||11.55 mL||23.09 mL|
|5 mM||1.15 mL||5.77 mL||11.55 mL|
|25 mM||0.23 mL||1.15 mL||2.31 mL|
References are publications that support the biological activity of the product.
Tulsiani et al (1982) Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of golgi mannosidase II. J.Biol.Chem. 257 7936 PMID: 6806288
Olden et al (1991) The potential importance of swainsonine in therapy for cancers and immunology. Pharmacol.Ther. 50 285 PMID: 1754603
Sun et al (2007) Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine. Phytomedicine 14 353 PMID: 17097281
If you know of a relevant reference for Swainsonine, please let us know.
View Related Products by Product Action
Keywords: Swainsonine, Swainsonine supplier, inhibitors, inhibits, α-mannosidase, alpha-mannosidase, II, Glycosylases, Carbohydrate, Metabolism, 3208, Tocris Bioscience
3 Citations for Swainsonine
Citations are publications that use Tocris products. Selected citations for Swainsonine include:
Skrenkova et al (2018) N-Glycosylation Regulates the Trafficking and Surface Mobility of GluN3A-Containing NMDA Receptors. Front Mol Neurosci 11 188 PMID: 29915530
Nacev et al (2011) The antifungal drug itracon. inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. J Biol Chem 286 44045 PMID: 22025615
Tareen et al (2014) Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells. Mol Ther 22 575 PMID: 24419083
Do you know of a great paper that uses Swainsonine from Tocris? Please let us know.
Reviews for Swainsonine
There are currently no reviews for this product. Be the first to review Swainsonine and earn rewards!
Have you used Swainsonine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)New
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells