You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for SD 1008
SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. Inhibits activation of STAT3, JAK2 and Src. Induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3.
Compound Libraries for SD 1008
Technical Data for SD 1008
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SD 1008
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for SD 1008
The following data is based on the product molecular weight 329.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.04 mL||15.18 mL||30.36 mL|
|5 mM||0.61 mL||3.04 mL||6.07 mL|
|10 mM||0.3 mL||1.52 mL||3.04 mL|
|50 mM||0.06 mL||0.3 mL||0.61 mL|
References for SD 1008
References are publications that support the biological activity of the product.
Duan et al (2007) 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel Janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells. Mol.Pharmacol. 72 1137 PMID: 17675586
If you know of a relevant reference for SD 1008, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: SD 1008, SD 1008 supplier, JAK2, STAT3, signaling, pathway, inhibitors, inhibits, activation, Src, SD1008, STAT, JAK, Kinase, 3035, Tocris Bioscience
Citations for SD 1008
Citations are publications that use Tocris products.
Currently there are no citations for SD 1008. Do you know of a great paper that uses SD 1008 from Tocris? Please let us know.
Reviews for SD 1008
There are currently no reviews for this product. Be the first to review SD 1008 and earn rewards!
Have you used SD 1008?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.