2-Pyridylethylamine dihydrochloride

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Cat.No. 2478 - 2-Pyridylethylamine dihydrochloride | C7H10N2.2HCl | CAS No. 3343-39-3
Description: H1 agonist
Chemical Name: 2-Pyridineethanamine dihydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Histamine H1 receptor agonist that produces vasoconstriction in vivo.

Compound Libraries

2-Pyridylethylamine dihydrochloride is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 195.09
Formula C7H10N2.2HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 3343-39-3
PubChem ID 201148
InChI Key GPIFKSYYILNJNR-UHFFFAOYSA-N
Smiles Cl.Cl.NCCC1=NC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 19.51 100
DMSO 9.75 50

Preparing Stock Solutions

The following data is based on the product molecular weight 195.09. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.13 mL 25.63 mL 51.26 mL
5 mM 1.03 mL 5.13 mL 10.25 mL
10 mM 0.51 mL 2.56 mL 5.13 mL
50 mM 0.1 mL 0.51 mL 1.03 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Martinez-Mir et al (1992) Effect of histamine and histamine analogues on human isolated myometrial strips. Br.J.Pharmacol. 107 528 PMID: 1358393

Arai and Chiba (1999) Endothelium-dependent vasodilation mechanisms by histamine in simian but not in canine femoral arterial branches. J.Auton.Pharmacol. 19 267 PMID: 10759332


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Keywords: 2-Pyridylethylamine dihydrochloride, 2-Pyridylethylamine dihydrochloride supplier, H1, receptor, agonists, Receptors, Histamine, histaminergic, 2478, Tocris Bioscience

1 Citation for 2-Pyridylethylamine dihydrochloride

Citations are publications that use Tocris products. Selected citations for 2-Pyridylethylamine dihydrochloride include:

Ashina et al (2015) Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo. Mol Med Rep 10 e0132367 PMID: 26158531


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