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Biological Activity for 2-Pyridylethylamine dihydrochloride
2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction in vivo.
Compound Libraries for 2-Pyridylethylamine dihydrochloride
Technical Data for 2-Pyridylethylamine dihydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 2-Pyridylethylamine dihydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for 2-Pyridylethylamine dihydrochloride
The following data is based on the product molecular weight 195.09. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.13 mL||25.63 mL||51.26 mL|
|5 mM||1.03 mL||5.13 mL||10.25 mL|
|10 mM||0.51 mL||2.56 mL||5.13 mL|
|50 mM||0.1 mL||0.51 mL||1.03 mL|
Product Datasheets for 2-Pyridylethylamine dihydrochloride
References for 2-Pyridylethylamine dihydrochloride
References are publications that support the biological activity of the product.
Martinez-Mir et al (1992) Effect of histamine and histamine analogues on human isolated myometrial strips. Br.J.Pharmacol. 107 528 PMID: 1358393
Arai and Chiba (1999) Endothelium-dependent vasodilation mechanisms by histamine in simian but not in canine femoral arterial branches. J.Auton.Pharmacol. 19 267 PMID: 10759332
If you know of a relevant reference for 2-Pyridylethylamine dihydrochloride, please let us know.
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Keywords: 2-Pyridylethylamine dihydrochloride, 2-Pyridylethylamine dihydrochloride supplier, H1, receptor, agonists, Receptors, Histamine, histaminergic, 2478, Tocris Bioscience
2 Citations for 2-Pyridylethylamine dihydrochloride
Citations are publications that use Tocris products. Selected citations for 2-Pyridylethylamine dihydrochloride include:
Jain et al (2018) Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. Am J Physiol Endocrinol Metab 315 E357 PMID: 29812984
Ashina et al (2015) Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo. Mol Med Rep 10 e0132367 PMID: 26158531
Do you know of a great paper that uses 2-Pyridylethylamine dihydrochloride from Tocris? Please let us know.
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Literature in this Area
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