Polyamine Supplement x1000 (lyophilized)

Pricing Availability   Qty
Description: Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
Datasheet
Citations
Reviews
Literature (4)

Biological Activity

Polyamine Supplement x1000 (lyophilized) is a media supplement comprising a lyophilized mixture of Putrescine, Spermine (Cat. No. 0958) and Spermidine. The product is used as a component of the CEPT cocktail, in combination with Emricasan (Cat. No. 7310), Chroman 1 (Cat. No. 7163) and trans-ISRIB (Cat. No. 5284) to enhance viability of human pluripotent stem cells (hPSCs) and their differentiated progeny. Polyamine Supplement x1000 (lyophilized) also improves survival of pluripotent and differentiated cells during cryopreservation, organoid formation, single-cell cloning, and genome editing.

NOTE: This reagent is provided lyophilized. To use prepare a 1000x stock solution by reconstituting vial contents in 5 mL of ddH2O and filter sterilize before use. Add 1 mL of sterile resuspended polyamines supplement (1000x stock) per 1 L of media.

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Chen et al (2021) A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nat.Methods 18 528 PMID: 33941937


If you know of a relevant reference for Polyamine Supplement x1000 (lyophilized), please let us know.

Keywords: Polyamine Supplement x1000 (lyophilized), Polyamine Supplement x1000 (lyophilized) supplier, cell, growth, stem, CEPT, cocktail, hPSCs, cryopreservation, pluripotent, differentiated, cells, organoid, single-cell, cloning, genome, editing, Stem, Cell, Proliferation, Reprogramming, Organoids, Biochemicals, and, Molecular, Biology, Cocktail, 7739, Tocris Bioscience

Citations for Polyamine Supplement x1000 (lyophilized)

Citations are publications that use Tocris products.

Currently there are no citations for Polyamine Supplement x1000 (lyophilized). Do you know of a great paper that uses Polyamine Supplement x1000 (lyophilized) from Tocris? Please let us know.

Reviews for Polyamine Supplement x1000 (lyophilized)

There are currently no reviews for this product. Be the first to review Polyamine Supplement x1000 (lyophilized) and earn rewards!

Have you used Polyamine Supplement x1000 (lyophilized)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Stem Cell Research Product Guide

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells Scientific Review

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow Poster

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells Poster

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.