PEN (mouse)

Pricing Availability Delivery Time Qty
Cat.No. 6308 - PEN (mouse) | Ser-Val-Asp-Gln-Asp-Leu-Gly-Pro-Glu-Val-Pro-Pro-Glu-Asn-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val | CAS No. 1236955-25-1
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.

Technical Data

M. Wt 2317.62
Formula C102H169N27O34
Sequence SVDQDLGPEVPPENVLGALLRV
Storage Store at -20°C
CAS Number 1236955-25-1
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in PBS (pH 7.4)

Preparing Stock Solutions

The following data is based on the product molecular weight 2317.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.43 mL 2.16 mL 4.31 mL
5 mM 0.09 mL 0.43 mL 0.86 mL
10 mM 0.04 mL 0.22 mL 0.43 mL
50 mM 0.01 mL 0.04 mL 0.09 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal. 9 ra43 PMID: 27117253


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Keywords: PEN (mouse), PEN (mouse) supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), 6308, Tocris Bioscience

Citations for PEN (mouse)

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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