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Submit ReviewProtease Inhibitor Cocktail I
Description: Protease inhibitor cocktail for mammalian cells
Biological Activity for Protease Inhibitor Cocktail I
Protease Inhibitor Cocktail I is a blend of protease inhibitors optimized for mammalian cells. Contains the following inhibitors: AEBSF HCl (100 mM), Aprotinin (80 μM), Bestatin (5 mM), E-64 (1.5 mM), Leupeptin (2 mM) and Pepstatin (1 mM). Cocktail is provided as 1 ml of 100X concentrate in DMSO.
Technical Data for Protease Inhibitor Cocktail I
| Storage | Store at -20°C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Protease Inhibitor Cocktail I
| Solubility | Soluble in DMSO (supplied pre-dissolved in 1ml DMSO) |
Product Datasheets for Protease Inhibitor Cocktail I
References for Protease Inhibitor Cocktail I
References are publications that support the biological activity of the product.
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Keywords: Protease Inhibitor Cocktail I, Protease Inhibitor Cocktail I supplier, AEBSF, Aprotinin, E-64, Bestatin, Leupeptin, Pepstatin, Biochemicals, and, Molecular, Biology, Reagents, in, Solution, 5500, Tocris Bioscience
1 Citation for Protease Inhibitor Cocktail I
Citations are publications that use Tocris products. Selected citations for Protease Inhibitor Cocktail I include:
Fitting et al (2014) Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in N+ influx, mitochondrial instability, and Ca2+ overload. J Biol Chem 34 12850 PMID: 25232120
Do you know of a great paper that uses Protease Inhibitor Cocktail I from Tocris? Please let us know.
Reviews for Protease Inhibitor Cocktail I
Average Rating: 5 (Based on 3 Reviews.)
Have you used Protease Inhibitor Cocktail I?
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Protein extraction HCT116.
By
Gabriele Strusi on 04/11/2025
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: HCT116
Protease inhibitor 100x added to Lysis Buffer 16 for Pluripotent stem cell markers proteome profiler.
Protein extraction from cancer-adipocytes co-culture.
By
Caterina Suelzu on 04/11/2025
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: SVF primary cells
Used for protein extraction from cancer-adipocytes co-culture. 100X dilution
Protein extraction addition.
By
Murali K Yanda on 09/27/2024
Assay Type: In Vitro
Species: protein lysis buffer
Cell Line/Tissue: 293
100X, one to one hundred dilute
We did WB with or without this inhibitor. We can see on the right lane, which is when we add inhibitor, showed protection of protein degradation.
