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Biological Activity for (S)-(-)-Propranolol hydrochloride
(S)-(-)-Propranolol hydrochloride is a more active enantiomer of the β-adrenoceptor antagonist propranolol.
Technical Data for (S)-(-)-Propranolol hydrochloride
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (S)-(-)-Propranolol hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for (S)-(-)-Propranolol hydrochloride
The following data is based on the product molecular weight 295.81. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.38 mL||16.9 mL||33.81 mL|
|5 mM||0.68 mL||3.38 mL||6.76 mL|
|10 mM||0.34 mL||1.69 mL||3.38 mL|
|50 mM||0.07 mL||0.34 mL||0.68 mL|
Product Datasheets for (S)-(-)-Propranolol hydrochloride
References for (S)-(-)-Propranolol hydrochloride
References are publications that support the biological activity of the product.
Barrett et al (1968) The biological properties of the optical isomers of propra. and their effects on cardiac arrhythmias. Br.J.Pharmacol. 34 43 PMID: 19108278
Bond et al (1967) Metabolism of propra. (Inderal) a potent, specific β-adrenergic receptor blocking agent. Nature 213 721 PMID: 6031788
If you know of a relevant reference for (S)-(-)-Propranolol hydrochloride, please let us know.
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1 Citation for (S)-(-)-Propranolol hydrochloride
Citations are publications that use Tocris products. Selected citations for (S)-(-)-Propranolol hydrochloride include:
Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Br J Pharmacol 329 350 PMID: 19144685
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.