(S)-(-)-Propranolol hydrochloride

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Cat.No. 0834 - (S)-(-)-Propranolol hydrochloride | C16H21NO2.HCl | CAS No. 4199-10-4
Description: β antagonist. More active enantiomer of propranolol (Cat. No. 0624)
Chemical Name: (S)-(-)-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

More active enantiomer of the β-adrenoceptor antagonist propranolol.

Racemate, R-enantiomer and Glycol Metabolite also available.

Technical Data

M. Wt 295.81
Formula C16H21NO2.HCl
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 4199-10-4
PubChem ID 165193
InChI Key ZMRUPTIKESYGQW-UQKRIMTDSA-N
Smiles CC(C)NC[C@]([H])(O)COC2=CC=CC1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 100 mM in water

References

References are publications that support the biological activity of the product.

Barrett et al (1968) The biological properties of the optical isomers of propra. and their effects on cardiac arrhythmias. Br.J.Pharmacol. 34 43 PMID: 19108278

Bond et al (1967) Metabolism of propra. (Inderal) a potent, specific β-adrenergic receptor blocking agent. Nature 213 721 PMID: 6031788


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1 Citation for (S)-(-)-Propranolol hydrochloride

Citations are publications that use Tocris products. Selected citations for (S)-(-)-Propranolol hydrochloride include:

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Br J Pharmacol 329 350 PMID: 19144685


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Literature in this Area

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