PSB 069

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Cat.No. 2573 - PSB 069 | C20H12N2O5ClSNa | CAS No. 78510-31-3
Description: Non-selective NTPDase inhibitor
Chemical Name: 1-Amino-4-(4-chlorophenyl)aminoanthraquinone-2-sulfonic acid sodium salt
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (2)

Biological Activity

Non-selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor. Reported to inhibit rat NTPDases 1, 2 and 3 with similar potencies.

Technical Data

M. Wt 450.83
Formula C20H12N2O5ClSNa
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 78510-31-3
PubChem ID 24868311
InChI Key KINIBOSGQKLOIT-UHFFFAOYSA-M
Smiles [Na+].NC1=C2C(=O)C3=CC=CC=C3C(=O)C2=C(NC2=CC=C(Cl)C=C2)C=C1S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.08 100

Preparing Stock Solutions

The following data is based on the product molecular weight 450.83. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.22 mL 11.09 mL 22.18 mL
5 mM 0.44 mL 2.22 mL 4.44 mL
10 mM 0.22 mL 1.11 mL 2.22 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Baqi et al (2009) Structure activity relationships of antraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases(E-NTPDases). Purinerg.Sig. 5 91


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Keywords: PSB 069, PSB 069 supplier, Non-Selective, NTPDase, inhibitors, inhibits, P-Type, ATPase, V-Type, E-Type, F-Type, ATPases, GTPases, PSB069, 2573, Tocris Bioscience

1 Citation for PSB 069

Citations are publications that use Tocris products. Selected citations for PSB 069 include:

Ibáñez et al (2012) A high throughput scintillation proximity imaging assay for protein methyltransferases. Comb Chem High Throughput Screen 15 359 PMID: 22256970


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Literature in this Area

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