|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 295.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.38 mL||16.9 mL||33.81 mL|
|5 mM||0.68 mL||3.38 mL||6.76 mL|
|10 mM||0.34 mL||1.69 mL||3.38 mL|
|50 mM||0.07 mL||0.34 mL||0.68 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Litwin et al (1999) Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure. Br.J.Pharmacol. 127 1671 PMID: 10455325
Xie et al (1998) The inhibitory effect of propranolol on ATP-sensitive potassium channels in neonatal rat heart. Br.J.Pharmacol. 123 599 PMID: 9517376
If you know of a relevant reference for Propranolol hydrochloride, please let us know.
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Keywords: β-adrenoceptor beta-adrenoceptors b-adrenoceptors b-adrenergic antagonists β-adrenergic beta-adrenergic Receptors Non-Selective β-blockers beta-blockers Non-selective Adrenergic Beta Receptors
9 Citations for Propranolol hydrochloride
Citations are publications that use Tocris products. Selected citations for Propranolol hydrochloride include:
Meitzen et al (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116 984 PMID: 21143600
Rankovic et al (2011) Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons. PLoS One 6 e27474 PMID: 22164209
Shi et al (2010) Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer. Purinergic Signal 9 269 PMID: 20939893
Gherbi et al (2015) Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation. FASEB J 29 2859 PMID: 25837585
Stoddart et al (2015) Application of BRET to monitor ligand binding to GPCRs. Nat Methods 12 661 PMID: 26030448
Patsouris et al (2015) Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans. Cereb Cortex 13 1538 PMID: 26586436
Hansen and Manahan-Vaughan (2015) Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors. Mol Cancer 25 1889 PMID: 24464942
Bucher et al (2014) Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab 34 1128 PMID: 24714037
Gherbi et al (2014) Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP. Br J Pharmacol 171 5431 PMID: 25052258
Do you know of a great paper that uses Propranolol hydrochloride from Tocris? If so please let us know.
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