PAMP-12 (human, porcine)

Pricing Availability   Qty

Save up to 40% on RUO Reagents with BIOSPRING24 (see details)

Description: Potent MRGPRX2 agonist
Purity: ≥95% (HPLC)

Biological Activity for PAMP-12 (human, porcine)

PAMP-12 (human, porcine) is a potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.

Technical Data for PAMP-12 (human, porcine)

M. Wt 1618.95
Formula C77H119N25O14

(Modification: Arg-12 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 196305-05-2
PubChem ID 16137959
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for PAMP-12 (human, porcine)

Solubility Soluble to 1 mg/ml in water

Product Datasheets for PAMP-12 (human, porcine)

Certificate of Analysis / Product Datasheet
Select another batch:

References for PAMP-12 (human, porcine)

References are publications that support the biological activity of the product.

Kamohara et al (2005) Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. Biochem.Biophys.Res.Commun. 330 1146 PMID: 15823563

Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID: 28288109

If you know of a relevant reference for PAMP-12 (human, porcine), please let us know.

View Related Products by Product Action

View all Mas-Related G Protein-Coupled Receptors Agonists

Keywords: PAMP-12 (human, porcine), PAMP-12 (human, porcine) supplier, PAMP-12, human, porcine, proadrenomedullin, ProAM, Mas, related, GPR, X2, MRGPRX2, agonists, agonism, potent, Mas-related, G, Protein-Coupled, Receptors, 6551, Tocris Bioscience

Citations for PAMP-12 (human, porcine)

Citations are publications that use Tocris products.

Currently there are no citations for PAMP-12 (human, porcine). Do you know of a great paper that uses PAMP-12 (human, porcine) from Tocris? Please let us know.

Reviews for PAMP-12 (human, porcine)

There are currently no reviews for this product. Be the first to review PAMP-12 (human, porcine) and earn rewards!

Have you used PAMP-12 (human, porcine)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review