Pomalidomide 4'-PEG2-acid

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Cat.No. 7212 - Pomalidomide 4'-PEG2-acid | C20H23N3O8 | CAS No. 2140807-17-4
Description: Cereblon ligand with PEG linker and terminal acid for onward chemistry
Chemical Name: 3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M. Wt 433.42
Formula C20H23N3O8
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 2140807-17-4
PubChem ID 134589759
InChI Key NKISJPXMSOQWER-UHFFFAOYSA-N
Smiles OC(CCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

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Keywords: Pomalidomide 4'-PEG2-acid, Pomalidomide 4'-PEG2-acid supplier, PROTAC, component, cereblon, E3, ubiquitin, ligase, PEG1, linker, polyethylene, glycol, conjugate, building, block, ligands, targeted, targeting, protein, degradation, TPD, Cereblon, Ligands, Plus, Linkers, 7212, Tocris Bioscience

Citations for Pomalidomide 4'-PEG2-acid

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