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Biological Activity for Pimonidazole
Pimonidazole is a hypoxia detection reagent. Labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
Technical Data for Pimonidazole
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Pimonidazole
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Pimonidazole
The following data is based on the product molecular weight 254.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.93 mL||19.66 mL||39.33 mL|
|5 mM||0.79 mL||3.93 mL||7.87 mL|
|10 mM||0.39 mL||1.97 mL||3.93 mL|
|50 mM||0.08 mL||0.39 mL||0.79 mL|
References for Pimonidazole
References are publications that support the biological activity of the product.
Sato et al (2016) Notch2 signaling regulates the proliferation of murine bone marrow-derived mesenchymal stem/stromal cells via c-Myc expression. PLoS One 11 e0165946 PMID: 27855169
Bennewith et al (2002) Orally administered pimonidazole to label hypoxic tumor cells. Cancer Res. 62 6827 PMID: 12460894
If you know of a relevant reference for Pimonidazole, please let us know.
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Keywords: Pimonidazole, Pimonidazole supplier, hypoxia, detection, detects, hypoxic, in, vivo, labels, labeling, Labels, and, Stains, Fluorescent, Cell, Indicators, Sensors, 6182, Tocris Bioscience
Citations for Pimonidazole
Citations are publications that use Tocris products.
Currently there are no citations for Pimonidazole. Do you know of a great paper that uses Pimonidazole from Tocris? Please let us know.
Reviews for Pimonidazole
Average Rating: 5 (Based on 1 Review.)
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Glioblstoma patient derived cell line E2 was cultured in a 3D model for 21 days and the level of hypoxia in the spheres were measured following treatment with Pimonidazole.
Literature in this Area
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Fluorescent Dyes and Probes Research Product GuideUpdated
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals