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Submit ReviewPAF (C16)
Discontinued Product
2940 has been discontinued.
View all Platelet-Activating Factor (PAF) Receptors products.
Description: Endogenous platelet-activating factor (PAF)
Alternative Names: Platelet-activating factor
Chemical Name: (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide
Biological Activity for PAF (C16)
PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
Technical Data for PAF (C16)
| M. Wt | 523.68 |
| Formula | C26H54NO7P |
| Storage | Store at -20°C |
| CAS Number | 74389-68-7 |
| PubChem ID | 108156 |
| InChI Key | HVAUUPRFYPCOCA-AREMUKBSSA-N |
| Smiles | CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for PAF (C16)
References for PAF (C16)
References are publications that support the biological activity of the product.
Oda et al (1985) Molecular species of platelet-activating factor generated by human neutrophils challenged with ionophore A23187. J.Immunol. 134 1090 PMID: 3917470
Archer et al (1988) Actions of platelet activating factor (PAF) homologues and their combinations on neutrophil chemokinesis and cutaneous inflammatory responses in man. J.Invest.Dermatol. 91 82 PMID: 3385217
Handa et al (1991) Vasorelaxant effect of C16-PAF and C18-PAF on renal blood flow and systemic blood pressure in the anesthetized rat. Life Sci. 49 747 PMID: 1875784
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Keywords: PAF (C16), PAF (C16) supplier, Endogenous, platelet-activating, factor, PAF, Receptors, Platelet-activating, Factor, (PAF), 2940, Tocris Bioscience
Citations for PAF (C16)
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Currently there are no citations for PAF (C16).
Reviews for PAF (C16)
Average Rating: 5 (Based on 1 Review.)
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Platelet activating factor (PAF).
By
Anonymous on 05/02/2018
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: microglia
Platelet activating factor (PAF) at 100nM induced a biphasic calcium response in microglia culture. Initial release from internal source and subsequent a sustained influx.