Progesterone

Pricing Availability Delivery Time Qty
Cat.No. 2835 - Progesterone | C21H30O2 | CAS No. 57-83-0
Description: Endogenous progesterone receptor agonist
Chemical Name: Pregn-4-ene-3,20-dione
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).

Technical Data

M. Wt 314.46
Formula C21H30O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 57-83-0
PubChem ID 5994
InChI Key RJKFOVLPORLFTN-LEKSSAKUSA-N
Smiles O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](C)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.45 100
ethanol 31.45 100

Preparing Stock Solutions

The following data is based on the product molecular weight 314.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.18 mL 15.9 mL 31.8 mL
5 mM 0.64 mL 3.18 mL 6.36 mL
10 mM 0.32 mL 1.59 mL 3.18 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Dong et al (2004) Characterization of a new class of selective nonsteroidal progesterone receptor agonist. Steroids 69 201 PMID: 15072922

Jerry (2007) Roles of estrogen and progesterone in breast cancer prevention. Breast Cancer Res. 9 102 PMID: 17381827


If you know of a relevant reference for Progesterone, please let us know.

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Keywords: Progesterone, supplier, Endogenous, progesterone, receptors, agonists, Progesterone, Receptor, Tocris Bioscience

2 Citations for Progesterone

Citations are publications that use Tocris products. Selected citations for Progesterone include:

White et al (2011) The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. J Neurosci 90 373 PMID: 21177701

Gibson et al (2016) Intracrine Androgens Enhance Decidualization and Modulate Expression of Human Endometrial Receptivity Genes. Sci Rep 6 19970 PMID: 26817618


Do you know of a great paper that uses Progesterone from Tocris? If so please let us know.

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Pathways for Progesterone

Protocols

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