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Biological Activity for Progesterone
Progesterone is an endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).
Technical Data for Progesterone
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Progesterone
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Progesterone
The following data is based on the product molecular weight 314.46. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.18 mL||15.9 mL||31.8 mL|
|5 mM||0.64 mL||3.18 mL||6.36 mL|
|10 mM||0.32 mL||1.59 mL||3.18 mL|
|50 mM||0.06 mL||0.32 mL||0.64 mL|
References for Progesterone
References are publications that support the biological activity of the product.
Dong et al (2004) Characterization of a new class of selective nonsteroidal progesterone receptor agonist. Steroids 69 201 PMID: 15072922
Jerry (2007) Roles of estrogen and progesterone in breast cancer prevention. Breast Cancer Res. 9 102 PMID: 17381827
If you know of a relevant reference for Progesterone, please let us know.
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Keywords: Progesterone, Progesterone supplier, Endogenous, progesterone, receptors, agonists, Progesterone, Receptor, 2835, Tocris Bioscience
6 Citations for Progesterone
Citations are publications that use Tocris products. Selected citations for Progesterone include:
El-Mayet et al (2019) Synergistic Activation of Bovine Herpesvirus 1 Productive Infection and Viral Regulatory Promoters by the Progesterone Receptor and Krüppel-Like Transcription Factor 15. J Virol 93 PMID: 30305353
White et al (2011) The serotonin transporter, gender, and 17β OE in the development of pulmonary arterial hypertension. J Neurosci 90 373 PMID: 21177701
Gibson et al (2018) Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. Fertil Steril 109 728 PMID: 29397924
Gibson et al (2018) SULFATION PATHWAYS: A role for steroid sulphatase in intracrine regulation of endometrial decidualisation. J Mol Endocrinol 61 M57 PMID: 29720512
Lou et al (2017) E2 Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1. Int J Biol Sci 13 434 PMID: 28529452
Gibson et al (2016) Intracrine Androgens Enhance Decidualization and Modulate Expression of Human Endometrial Receptivity Genes. Sci Rep 6 19970 PMID: 26817618
Do you know of a great paper that uses Progesterone from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.