You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent and selective DGAT-1 inhibitor (IC50 = 19 nM). Exhibits >1000-fold selectivity for DGAT-1 over DGAT-2, and no significant activity against a range of other enzymes, ion channels and receptors. Reduces plasma triglyceride levels in a rat lipid challenge model. Orally bioavailable.
Sold for research purposes under agreement from Pfizer Inc.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 396.44. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||12.61 mL||63.06 mL||126.12 mL|
|1 mM||2.52 mL||12.61 mL||25.22 mL|
|2 mM||1.26 mL||6.31 mL||12.61 mL|
|10 mM||0.25 mL||1.26 mL||2.52 mL|
References are publications that support the biological activity of the product.
Dow et al (2011) Discovery of PF-04620110, a potent, selective, and orally bioavailable inhibitor of DGAT-1. ACS Med.Chem.Lett. 2 407 PMID: 24900321
If you know of a relevant reference for PF 04620110, please let us know.
View Related Products by Product Action
Keywords: PF 04620110, PF 04620110 supplier, PF04620110, potent, selective, orally, bioavailable, inhibitors, inhibits, DGAT-1, Diacylglycerol, acyltransferase, O-Acyltransferase, 5863, Tocris Bioscience
Citations for PF 04620110
Citations are publications that use Tocris products.
Currently there are no citations for PF 04620110. Do you know of a great paper that uses PF 04620110 from Tocris? Please let us know.
Reviews for PF 04620110
There are currently no reviews for this product. Be the first to review PF 04620110 and earn rewards!
Have you used PF 04620110?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image