You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for PF 04628935
PF 04628935 is a potent ghrelin receptor inverse agonist (IC50 = 4.6 nM). Orally bioavailable and exhibits reasonable brain penetration.
Sold for research purposes under agreement from Pfizer Inc.
Compound Libraries for PF 04628935
Technical Data for PF 04628935
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for PF 04628935
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for PF 04628935
The following data is based on the product molecular weight 496.03. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.03 mL||20.16 mL||40.32 mL|
|2.5 mM||0.81 mL||4.03 mL||8.06 mL|
|5 mM||0.4 mL||2.02 mL||4.03 mL|
|25 mM||0.08 mL||0.4 mL||0.81 mL|
References for PF 04628935
References are publications that support the biological activity of the product.
Kung et al (2012) Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor. Bioorg.Med.Chem.Lett. 22 5410 PMID: 22677316
If you know of a relevant reference for PF 04628935, please let us know.
View Related Products by Product Action
Keywords: PF 04628935, PF 04628935 supplier, PF04628935, inverse, agonists, agonism, ghrelin, orally, bioavailable, potent, Ghrelin, Receptors, 6347, Tocris Bioscience
Citations for PF 04628935
Citations are publications that use Tocris products.
Currently there are no citations for PF 04628935. Do you know of a great paper that uses PF 04628935 from Tocris? Please let us know.
Reviews for PF 04628935
There are currently no reviews for this product. Be the first to review PF 04628935 and earn rewards!
Have you used PF 04628935?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.