Pomalidomide 4'-PEG5-azide

Pricing Availability   Qty
Description: Cereblon ligand with PEG linker and terminal azide for onward chemistry
Chemical Name: 4-[(17-Azido-3,6,9,12,15-pentaoxaheptadecyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity: ≥95% (HPLC)
Literature (2)

Biological Activity for Pomalidomide 4'-PEG5-azide

Pomalidomide 4'-PEG5-azide is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG5 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines for Pomalidomide 4'-PEG5-azide

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Pomalidomide 4'-PEG5-azide

M. Wt 562.58
Formula C25H34N6O9
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 2624181-61-7
PubChem ID 155292081

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Pomalidomide 4'-PEG5-azide

References for Pomalidomide 4'-PEG5-azide

References are publications that support the biological activity of the product.

If you know of a relevant reference for Pomalidomide 4'-PEG5-azide, please let us know.

Keywords: Pomalidomide 4'-PEG5-azide, Pomalidomide 4'-PEG5-azide supplier, PROTAC, cereblon, E3, ubiquitin, ligase, PEG5, linker, conjugate, PROTACs, polyethylene, glycol, terminal, azide, building, blocks, components, Cereblon, Ligands, Plus, Linkers, 7437, Tocris Bioscience

Citations for Pomalidomide 4'-PEG5-azide

Citations are publications that use Tocris products.

Currently there are no citations for Pomalidomide 4'-PEG5-azide. Do you know of a great paper that uses Pomalidomide 4'-PEG5-azide from Tocris? Please let us know.

Reviews for Pomalidomide 4'-PEG5-azide

There are currently no reviews for this product. Be the first to review Pomalidomide 4'-PEG5-azide and earn rewards!

Have you used Pomalidomide 4'-PEG5-azide?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Targeted Protein Degradation Research Product Guide

Targeted Protein Degradation Research Product Guide

This brochure highlights the tools and services available from Bio-Techne to support Targeted Protein Degradation research, including:

  • Active Degraders
  • TAG Degradation Platform
  • Degrader Building Blocks
  • Ubiquitin-Proteasome System Proteins
  • Assays for Protein Degradation
Targeted Protein Degradation Poster

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia