Prostaglandin F

Pricing Availability   Qty
Description: Naturally-occurring prostanoid; potent vasoconstrictor
Chemical Name: 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
Purity: ≥98% (HPLC)

Biological Activity for Prostaglandin F

Prostaglandin F2α is a prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.

Technical Data for Prostaglandin F

M. Wt 475.62
Formula C20H34O5.C4H11NO3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 38562-01-5
PubChem ID 5282415
Smiles O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Prostaglandin F

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 47.56 100
ethanol 47.56 100

Preparing Stock Solutions for Prostaglandin F

The following data is based on the product molecular weight 475.62. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.1 mL 10.51 mL 21.03 mL
5 mM 0.42 mL 2.1 mL 4.21 mL
10 mM 0.21 mL 1.05 mL 2.1 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

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Product Datasheets for Prostaglandin F

Certificate of Analysis / Product Datasheet
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References for Prostaglandin F

References are publications that support the biological activity of the product.

Samuelsson et al (1978) Prostaglandins and throboxanes. Annu.Rev.Biochem. 47 997 PMID: 209733

Girsh and Dekel (2002) Involvement of endothelin-1 and its receptors in PGF-induced luteolysis in the rat. Mol.Reprod.Dev. 63 71 PMID: 12211063

Lai et al (1996) Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol. 271 2197

If you know of a relevant reference for Prostaglandin F, please let us know.

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Citations for Prostaglandin F

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