Prostaglandin F2α

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Cat.No. 4214 - Prostaglandin F2alpha | C20H34O5.C4H11NO3 | CAS No. 38562-01-5
Description: Naturally-occurring prostanoid; potent vasoconstrictor
Chemical Name: 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (6)

Biological Activity

Prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.

Technical Data

M. Wt 475.62
Formula C20H34O5.C4H11NO3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 38562-01-5
PubChem ID 5282415
InChI Key IYGXEHDCSOYNKY-RZHHZEQLSA-N
Smiles O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.56 100
ethanol 47.56 100

Preparing Stock Solutions

The following data is based on the product molecular weight 475.62. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.1 mL 10.51 mL 21.03 mL
5 mM 0.42 mL 2.1 mL 4.21 mL
10 mM 0.21 mL 1.05 mL 2.1 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Samuelsson et al (1978) Prostaglandins and throboxanes. Annu.Rev.Biochem. 47 997 PMID: 209733

Girsh and Dekel (2002) Involvement of endothelin-1 and its receptors in PGF-induced luteolysis in the rat. Mol.Reprod.Dev. 63 71 PMID: 12211063

Lai et al (1996) Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol. 271 2197


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Citations for Prostaglandin F2α

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Literature in this Area

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