Prostaglandin F2α

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Cat.No. 4214 - Prostaglandin F2alpha | C20H34O5.C4H11NO3 | CAS No. 38562-01-5
Description: Naturally-occurring prostanoid; potent vasoconstrictor
Chemical Name: 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.

Technical Data

M. Wt 475.62
Formula C20H34O5.C4H11NO3
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 38562-01-5
PubChem ID 5282415
InChI Key IYGXEHDCSOYNKY-RZHHZEQLSA-N
Smiles O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.56 100
ethanol 47.56 100

Preparing Stock Solutions

The following data is based on the product molecular weight 475.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.1 mL 10.51 mL 21.03 mL
5 mM 0.42 mL 2.1 mL 4.21 mL
10 mM 0.21 mL 1.05 mL 2.1 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Samuelsson et al (1978) Prostaglandins and throboxanes. Annu.Rev.Biochem. 47 997 PMID: 209733

Girsh and Dekel (2002) Involvement of endothelin-1 and its receptors in PGF-induced luteolysis in the rat. Mol.Reprod.Dev. 63 71 PMID: 12211063

Lai et al (1996) Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol. 271 2197 PMID:


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Citations for Prostaglandin F2α

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Pathways for Prostaglandin F2α

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