Potent, selective P2Y2 agonist (EC50 = 0.134 μM). Displays >60-fold selectivity versus P2Y4 and P2Y6 receptors.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in water (supplied pre-dissolved at a concentration of 10mM)|
References are publications that support the biological activity of the product.
El-Tayeb et al (2011) Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J.Med.Chem. 54 2878 PMID: 21417463
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Keywords: PSB 1114, PSB 1114 supplier, PSB1114, P2Y2, receptors, agonist, purinergic, P2Y, 2, agonists, purinoceptors, Purinergic, Receptors, 4333, Tocris Bioscience
1 Citation for PSB 1114
Citations are publications that use Tocris products. Selected citations for PSB 1114 include:
Roshanravan and Dryer (2014) ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species. Neuropsychopharmacology 306 F1088 PMID: 24553432
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