PSB 1114

Pricing Availability   Qty
Description: Potent, selective P2Y2 agonist
Chemical Name: 4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (5)

Biological Activity for PSB 1114

PSB 1114 is a potent, selective P2Y2 agonist (EC50 = 0.134 μM). Displays >60-fold selectivity versus P2Y4 and P2Y6 receptors.

Technical Data for PSB 1114

M. Wt 622.14
Formula C10H11F2N2Na4O13P3S
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1657025-60-9
PubChem ID 90488930
InChI Key KATPYMNMKKBLAH-GENVZAMMSA-J
Smiles [Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)C(O[C@@H]1COP([O-])(=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O)N1C=CC(=S)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for PSB 1114

Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Product Datasheets for PSB 1114

Certificate of Analysis / Product Datasheet
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References for PSB 1114

References are publications that support the biological activity of the product.

El-Tayeb et al (2011) Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J.Med.Chem. 54 2878 PMID: 21417463


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Keywords: PSB 1114, PSB 1114 supplier, PSB1114, P2Y2, receptors, agonist, purinergic, P2Y, 2, agonists, purinoceptors, Purinergic, Receptors, 4333, Tocris Bioscience

1 Citation for PSB 1114

Citations are publications that use Tocris products. Selected citations for PSB 1114 include:

Roshanravan and Dryer (2014) ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species. Neuropsychopharmacology 306 F1088 PMID: 24553432


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Reviews for PSB 1114

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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