Thrombin Receptor Agonist Peptide
Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 μM) and secretion.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 0.90 mg/ml in water|
References are publications that support the biological activity of the product.
Huang et al (1991) 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 266 18435 PMID: 1655750
Vassallo et al (1992) Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 267 6081 PMID: 1313429
Vu et al (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64 1057 PMID: 1672265
If you know of a relevant reference for Thrombin Receptor Agonist Peptide, please let us know.
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Keywords: Thrombin Receptor Agonist Peptide, Thrombin Receptor Agonist Peptide supplier, Causes, platelet, aggregation, secretion, PAR, Receptors, Protease-Activated, thrombin, receptor, agonists, TRAP, 1185, Tocris Bioscience
2 Citations for Thrombin Receptor Agonist Peptide
Citations are publications that use Tocris products. Selected citations for Thrombin Receptor Agonist Peptide include:
Tripathi et al (2014) Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci 55 3912 PMID: 24876278
White et al (2015) A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Endocrinol 194 142 PMID: 25429068
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