Near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than luciferase. 100-1000 times brighter in vivo than conventional systems. Allows non-invasive visualization of single cells deep inside freely moving animals. Orally bioavailable and brain penetrant.
The batch molecular weight of the product may vary significantly due to hydration level. Please refer to the Certificate of Analysis for the current batch.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||5||15 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 338.85. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.3 mM||9.84 mL||49.19 mL||98.37 mL|
|1.5 mM||1.97 mL||9.84 mL||19.67 mL|
|3 mM||0.98 mL||4.92 mL||9.84 mL|
|15 mM||0.2 mL||0.98 mL||1.97 mL|
References are publications that support the biological activity of the product.
Kuchimaru et al (2016) A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging. Nat. Commun. 7 11856 PMID: 27297211
Nasu et al (2018) Unnaturally aglow with a bright inner light. Science 359 868 PMID: 29472468
Iwano et al (2018) Single-cell bioluminescence imaging of deep tissue in freely moving animals. Science 359 935 PMID: 29472486
If you know of a relevant reference for TokeOni, please let us know.
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