You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent and reversible fatty acid desaturase 1 (FADS1; Δ5 desaturase) inhibitor (IC50 values are 1.9 nM and 2.1 nM in human and rat hepatocyte cell lines, respectively). Exhibits >300 fold selectivity for FADS1 over FADS2 (Δ6 desaturase). Inhibits arachidonic acid production in rat and human hepatocyte cell lines. Orally bioavailable.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 443.46. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.25 mL||11.27 mL||22.55 mL|
|5 mM||0.45 mL||2.25 mL||4.51 mL|
|10 mM||0.23 mL||1.13 mL||2.25 mL|
|50 mM||0.05 mL||0.23 mL||0.45 mL|
References are publications that support the biological activity of the product.
Miyahisa et al (2016) T-3364366 targets the desaturase domain of delta-5 desaturase with nanomolar potency and a multihour residence time. ACS Med.Chem.Lett. 7 868 PMID: 27660693
If you know of a relevant reference for T 3364366, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: T 3364366, T 3364366 supplier, T3364366, FADS1, inhibitors, inhibits, potent, reversible, delta5, desaturase, arachidonic, acid, anti-inflammatory, acyl-lipid(8-3), Other, Lipid, Metabolism, Oxygenases/Oxidases, 6106, Tocris Bioscience
Citations for T 3364366
Citations are publications that use Tocris products.
Currently there are no citations for T 3364366. Do you know of a great paper that uses T 3364366 from Tocris? Please let us know.
Reviews for T 3364366
There are currently no reviews for this product. Be the first to review T 3364366 and earn rewards!
Have you used T 3364366?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image