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Taxol Janelia Fluor® 646 is a red fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Taxol Janelia Fluor® 646 is fluorogenic: fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation maximum = 655 nm; emission maximum = 671 nm.
For more information on how Taxol-Janelia Fluor® 646 may be used, see our protocol.
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus
Application of Taxol Janelia Fluor® 646, dye on COS7 cells; COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope.
All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 1403.62. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||3.56 mL||17.81 mL||35.62 mL|
|1 mM||0.71 mL||3.56 mL||7.12 mL|
|2 mM||0.36 mL||1.78 mL||3.56 mL|
|10 mM||0.07 mL||0.36 mL||0.71 mL|
References are publications that support the biological activity of the product.
If you know of a relevant reference for Taxol Janelia Fluor® 646, please let us know.
Keywords: Taxol Janelia Fluor 646, Taxol Janelia Fluor 646 supplier, red, fluorescent, taxol, derivative, cytoskeletal, probes, microtubules, fluorogenic, Organelle, and, Cell, Structure, Stains, Microtubule, Probes, 6266, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Taxol Janelia Fluor® 646 include:
Lemaître et al (2021) Capturing T lymphocytes' dynamic interactions with human neural cells using time-lapse microscopy. Front.Immunol. 12 PMID: 33968073
Do you know of a great paper that uses Taxol Janelia Fluor® 646 from Tocris? Please let us know.
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The following protocol features additional information for the use of Taxol Janelia Fluor® 646 (Cat. No. 6266).
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our: