6 TMR Tre

Pricing Availability   Qty
Description: Fluorescent trehalose; selectively labels mycobacterial cell envelope
Chemical Name: 6-[4(3)-[3,6-bis(dimethylamino)xanthylium-9-yl]-3(4)-carboxybenzoyl]amino-6-deoxy-α,α-D-trehalose
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity for 6 TMR Tre

6 TMR Tre is a fluorescent trehalose conjugate for imaging bacterial cell envelope. Selectively labels mycobacterial trehalose monomycolate (TMM). Allows real-time visualization of peptidoglycan and monomycolate dynamics at the single-cell level. Suitable for use with confocal and super-resolution microscopy.

Optical Data for 6 TMR Tre

Emission Color Yellow
λabs 532 nm
λem 580 nm

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Technical Data for 6 TMR Tre

M. Wt 753.75
Formula C37H43N3O14
Storage Store at -20°C
Purity ≥98% (HPLC)
Smiles [H][C@]1([C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CNC(C3=CC(C([O-])=O)=C(C4=C(C=C/5)C(OC6=C4C=CC(N(C)C)=C6)=CC5=[N+](C)/C)C=C3)=O)O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 6 TMR Tre

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 5 7

Preparing Stock Solutions for 6 TMR Tre

The following data is based on the product molecular weight 753.75. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.07 mM 18.95 mL 94.76 mL 189.53 mL
0.35 mM 3.79 mL 18.95 mL 37.91 mL
0.7 mM 1.9 mL 9.48 mL 18.95 mL
3.5 mM 0.38 mL 1.9 mL 3.79 mL

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References for 6 TMR Tre

References are publications that support the biological activity of the product.

Rodriguez-Rivera et al (2018) Acute modulation of mycobacterial cell envelope biogenesis by front-line tuberculosis drugs. Angew.Chem.Int.Ed. 57 5267 PMID: 29392891

If you know of a relevant reference for 6 TMR Tre, please let us know.

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Citations for 6 TMR Tre

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Literature in this Area

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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