6 TMR Tre

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Cat.No. 6802 - 6 TMR Tre | C37H43N3O14
Description: Fluorescent trehalose; selectively labels mycobacterial cell envelope
Chemical Name: 6-[4(3)-[3,6-bis(dimethylamino)xanthylium-9-yl]-3(4)-carboxybenzoyl]amino-6-deoxy-α,α-D-trehalose
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity

Fluorescent trehalose conjugate for imaging bacterial cell envelope. Selectively labels mycobacterial trehalose monomycolate (TMM). Allows real-time visualization of peptidoglycan and monomycolate dynamics at the single-cell level. Suitable for use with super-resolution microscopy.

Technical Data

M. Wt 753.75
Formula C37H43N3O14
Storage Store at -20°C
Purity ≥98% (HPLC)
Smiles [H][C@]1([C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CNC(C3=CC(C([O-])=O)=C(C4=C(C=C/5)C(OC6=C4C=CC(N(C)C)=C6)=CC5=[N+](C)/C)C=C3)=O)O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 5 7

Preparing Stock Solutions

The following data is based on the product molecular weight 753.75. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.07 mM 18.95 mL 94.76 mL 189.53 mL
0.35 mM 3.79 mL 18.95 mL 37.91 mL
0.7 mM 1.9 mL 9.48 mL 18.95 mL
3.5 mM 0.38 mL 1.9 mL 3.79 mL

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References are publications that support the biological activity of the product.

Rodriguez-Rivera et al (2018) Acute modulation of mycobacterial cell envelope biogenesis by front-line tuberculosis drugs. Angew.Chem.Int.Ed. 57 5267 PMID: 29392891

If you know of a relevant reference for 6 TMR Tre, please let us know.

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