Tetraethylammonium chloride
Biological Activity
Non-selective K+ channel blocker.
Technical Data
| M. Wt | 165.2 |
| Formula | C8H20ClN |
| Storage | Desiccate at RT |
| CAS Number | 56-34-8 |
| PubChem ID | 5946 |
| InChI Key | YMBCJWGVCUEGHA-UHFFFAOYSA-M |
| Smiles | CC[N+](CC)(CC)CC.[Cl-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Product Datasheets
References
References are publications that support the biological activity of the product.
Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400
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Keywords: Tetraethylammonium chloride, Tetraethylammonium chloride supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Channels, 3068, Tocris Bioscience
5 Citations for Tetraethylammonium chloride
Citations are publications that use Tocris products. Selected citations for Tetraethylammonium chloride include:
Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342
Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694
Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Stem Cell Reports 110 16622 PMID: 24046374
Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543
Borgs et al (2016) Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports 6 33377 PMID: 27640816
Do you know of a great paper that uses Tetraethylammonium chloride from Tocris? Please let us know.
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Tetraethylammonium was used to identify percentage blocking on potassium channel.The product shows relatively low blocking action on potassium channels. It works good on sterile conditions and the data pattern is quite similar.
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