Tetraethylammonium chloride
Biological Activity
Non-selective K+ channel blocker.
Technical Data
| M. Wt | 165.2 |
| Formula | C8H20ClN |
| Storage | Desiccate at RT |
| CAS Number | 56-34-8 |
| PubChem ID | 5946 |
| InChI Key | YMBCJWGVCUEGHA-UHFFFAOYSA-M |
| Smiles | CC[N+](CC)(CC)CC.[Cl-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 165.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.05 mL | 30.27 mL | 60.53 mL |
| 5 mM | 1.21 mL | 6.05 mL | 12.11 mL |
| 10 mM | 0.61 mL | 3.03 mL | 6.05 mL |
| 50 mM | 0.12 mL | 0.61 mL | 1.21 mL |
Molarity Calculator
Reconstitution Calculator
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400
If you know of a relevant reference for Tetraethylammonium chloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Tetraethylammonium chloride, supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Potassium, Channels, Tocris Bioscience
4 Citations for Tetraethylammonium chloride
Citations are publications that use Tocris products. Selected citations for Tetraethylammonium chloride include:
Borgs et al (2016) Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports 6 33377 PMID: 27640816
Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342
Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694
Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Stem Cell Reports 110 16622 PMID: 24046374
Do you know of a great paper that uses Tetraethylammonium chloride from Tocris? If so please let us know.
Literature in this Area
Cardiovascular Research Product Guide
A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:
- Hypertension
- Thrombosis and Hemostasis
- Atherosclerosis
- Myocardial Infarction
- Ischemia/Reperfusion Injury
- Arrhythmias
- Heart Failure
Pain Research Product Guide
A collection of over 250 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Pain Poster
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.
