Tetraethylammonium chloride
Biological Activity
Non-selective K+ channel blocker.
Technical Data
| M. Wt | 165.2 |
| Formula | C8H20ClN |
| Storage | Desiccate at RT |
| CAS Number | 56-34-8 |
| PubChem ID | 5946 |
| InChI Key | YMBCJWGVCUEGHA-UHFFFAOYSA-M |
| Smiles | CC[N+](CC)(CC)CC.[Cl-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 165.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.05 mL | 30.27 mL | 60.53 mL |
| 5 mM | 1.21 mL | 6.05 mL | 12.11 mL |
| 10 mM | 0.61 mL | 3.03 mL | 6.05 mL |
| 50 mM | 0.12 mL | 0.61 mL | 1.21 mL |
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References
References are publications that support the biological activity of the product.
Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400
If you know of a relevant reference for Tetraethylammonium chloride, please let us know.
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Keywords: Tetraethylammonium chloride, Tetraethylammonium chloride supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Channels, 3068, Tocris Bioscience
5 Citations for Tetraethylammonium chloride
Citations are publications that use Tocris products. Selected citations for Tetraethylammonium chloride include:
Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342
Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694
Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Stem Cell Reports 110 16622 PMID: 24046374
Borgs et al (2016) Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports 6 33377 PMID: 27640816
Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543
Do you know of a great paper that uses Tetraethylammonium chloride from Tocris? Please let us know.
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