Tetraethylammonium chloride

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Cat.No. 3068 - Tetraethylammonium chloride | C8H20ClN | CAS No. 56-34-8
Description: Non-selective K+ channel blocker
Alternative Names: TEA
Chemical Name: N,N,N,N-Tetraethylammonium chloride
Datasheet
Citations (7)
Reviews (1)
Literature (5)

Biological Activity

Non-selective K+ channel blocker.

Technical Data

M. Wt 165.2
Formula C8H20ClN
Storage Desiccate at RT
CAS Number 56-34-8
PubChem ID 5946
InChI Key YMBCJWGVCUEGHA-UHFFFAOYSA-M
Smiles CC[N+](CC)(CC)CC.[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 100 mM in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400


If you know of a relevant reference for Tetraethylammonium chloride, please let us know.

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Keywords: Tetraethylammonium chloride, Tetraethylammonium chloride supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Channels, 3068, Tocris Bioscience

7 Citations for Tetraethylammonium chloride

Citations are publications that use Tocris products. Selected citations for Tetraethylammonium chloride include:

Zhang et al (2019) A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. J Biol Chem PMID: 30792309

Borgs et al (2016) DArgic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports 6 33377 PMID: 27640816

Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543

Collins et al (2018) Reciprocal Circuits Linking the Prefrontal Cortex with Dorsal and Ventral Thalamic Nuclei. Neuron 98 366 PMID: 29628187

Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342

Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694

Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Stem Cell Reports 110 16622 PMID: 24046374


Do you know of a great paper that uses Tetraethylammonium chloride from Tocris? Please let us know.

Reviews for Tetraethylammonium chloride

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Tetraethylammonium was used to identify percentage blocking on potassium channel.
By Anonymous on 10/31/2018
Assay Type: In Vitro
Species: Human

Tetraethylammonium was used to identify percentage blocking on potassium channel.The product shows relatively low blocking action on potassium channels. It works good on sterile conditions and the data pattern is quite similar.

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Literature in this Area

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*Please note that Tocris will only send literature to established scientific business / institute addresses.


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