Tetraethylammonium chloride

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Description: Non-selective K+ channel blocker
Alternative Names: TEA
Chemical Name: N,N,N,N-Tetraethylammonium chloride
Datasheet
Citations (7)
Reviews (1)

Biological Activity for Tetraethylammonium chloride

Tetraethylammonium chloride is a non-selective K+ channel blocker.

Technical Data for Tetraethylammonium chloride

M. Wt 165.2
Formula C8H20ClN
Storage Desiccate at RT
CAS Number 56-34-8
PubChem ID 5946
InChI Key YMBCJWGVCUEGHA-UHFFFAOYSA-M
Smiles CC[N+](CC)(CC)CC.[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Tetraethylammonium chloride

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for Tetraethylammonium chloride

The following data is based on the product molecular weight 165.2. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.05 mL 30.27 mL 60.53 mL
5 mM 1.21 mL 6.05 mL 12.11 mL
10 mM 0.61 mL 3.03 mL 6.05 mL
50 mM 0.12 mL 0.61 mL 1.21 mL

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Product Datasheets for Tetraethylammonium chloride

Certificate of Analysis / Product Datasheet
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References for Tetraethylammonium chloride

References are publications that support the biological activity of the product.

Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400


If you know of a relevant reference for Tetraethylammonium chloride, please let us know.

View Related Products by Product Action

View all Voltage-gated Potassium (KV) Channel Blockers

Keywords: Tetraethylammonium chloride, Tetraethylammonium chloride supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Channels, 3068, Tocris Bioscience

7 Citations for Tetraethylammonium chloride

Citations are publications that use Tocris products. Selected citations for Tetraethylammonium chloride include:

Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543

Zhang et al (2019) A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. J Biol Chem PMID: 30792309

Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342

Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694


Do you know of a great paper that uses Tetraethylammonium chloride from Tocris? Please let us know.

Reviews for Tetraethylammonium chloride

Average Rating: 5 (Based on 1 Review.)

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Tetraethylammonium was used to identify percentage blocking on potassium channel.
By Anonymous on 10/31/2018
Assay Type: In Vitro
Species: Human

Tetraethylammonium was used to identify percentage blocking on potassium channel.The product shows relatively low blocking action on potassium channels. It works good on sterile conditions and the data pattern is quite similar.

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