T3

Pricing Availability   Qty
Cat.No. 6666 - T3 | C15H12I3NO4 | CAS No. 6893-02-3
Description: Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats. Used in protocols to generate cortical spheroids from hPSCs. Sodium salt (Cat. No. 5552) also available.

Technical Data

M. Wt 650.97
Formula C15H12I3NO4
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 6893-02-3
PubChem ID 5920
InChI Key AUYYCJSJGJYCDS-LBPRGKRZSA-N
Smiles N[C@H](C(O)=O)CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(C=C2)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.55 50

Preparing Stock Solutions

The following data is based on the product molecular weight 650.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.07 mL 15.36 mL 30.72 mL
2.5 mM 0.61 mL 3.07 mL 6.14 mL
5 mM 0.31 mL 1.54 mL 3.07 mL
25 mM 0.06 mL 0.31 mL 0.61 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Marta et al (1998) Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J.Neurosci.Res. 53 251 PMID: 9671982

Madhavan et al (2018) Induction of myelinating oligodendrocytes in human cortical spheroids. Nat Methods. 15 700 PMID: 30046099


If you know of a relevant reference for T3, please let us know.

Keywords: T3, T3 supplier, triiodothyronine, thyroid, hormone, oligodendroglial, precursors, differentiation, cortical, organoids, Other, Nuclear, Receptors, Differentiation, Products, 6666, Tocris Bioscience

Citations for T3

Citations are publications that use Tocris products.

Currently there are no citations for T3. Do you know of a great paper that uses T3 from Tocris? Please let us know.

Reviews for T3

There are currently no reviews for this product. Be the first to review T3 and earn rewards!

Have you used T3?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
  • Retinoic Acid Receptors
  • Retinoid X Receptors
  • Vitamin D Receptors