Thalidomide 4'-ether-alkylC2-acid

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Cat.No. 7329 - Thalidomide 4'-ether-alkylC2-acid | C16H14N2O7 | CAS No. 2369068-42-6
Description: Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name: 3-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]propanoic acid
Purity: ≥95% (HPLC)
Literature (2)

Biological Activity for Thalidomide 4'-ether-alkylC2-acid

Thalidomide 4'-ether-alkylC2-acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines for Thalidomide 4'-ether-alkylC2-acid

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Thalidomide 4'-ether-alkylC2-acid

M. Wt 346.3
Formula C16H14N2O7
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 2369068-42-6
PubChem ID 139370805
Smiles OC(CCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Thalidomide 4'-ether-alkylC2-acid

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Keywords: Thalidomide 4'-ether-alkylC2-acid, Thalidomide 4'-ether-alkylC2-acid supplier, PROTAC, component, cereblon, E3, ubiquitin, ligase, AlkylC2, linker, conjugate, building, block, ligands, targeted, targeting, protein, degradation, TPD, components, Cereblon, Ligands, Plus, Linkers, 7329, Tocris Bioscience

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