TC OT 39
Potent non-peptide oxytocin receptor partial agonist (EC50 values are 33 nM and 850 nM for the oxytocin receptor and V2 vasopressin receptor respectively). Also a V1a vasopressin receptor antagonist (Ki = 330 nM). Active in vivo in a rat model of uterine response.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO|
References are publications that support the biological activity of the product.
Frantz et al (2010) Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist. J.Med.Chem. 53 1546 PMID: 20104850
Pitt et al (2004) Non-peptide oxytocin agonists. Bioorg.Med.Chem.Lett. 14 4585 PMID: 15357997
If you know of a relevant reference for TC OT 39, please let us know.
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Keywords: TC OT 39, TC OT 39 supplier, TCOT39, nonpeptide, oxytocin, receptors, partial, agonists, vasopressin, potent, V1A, V2, Oxytocin, Receptors, Vasopressin, 4625, Tocris Bioscience
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