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Description: Highly potent NMDA agonist
Purity: ≥98% (HPLC)
Literature (5)

Biological Activity for (RS)-(Tetrazol-5-yl)glycine

(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.

Technical Data for (RS)-(Tetrazol-5-yl)glycine

M. Wt 143.1
Formula C3H5N5O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 138199-51-6
PubChem ID 126383
Smiles NC(C(O)=O)C1=NN=NN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for (RS)-(Tetrazol-5-yl)glycine

Solvent Max Conc. mg/mL Max Conc. mM
water 50

Preparing Stock Solutions for (RS)-(Tetrazol-5-yl)glycine

The following data is based on the product molecular weight 143.1. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 13.98 mL 69.88 mL 139.76 mL
2.5 mM 2.8 mL 13.98 mL 27.95 mL
5 mM 1.4 mL 6.99 mL 13.98 mL
25 mM 0.28 mL 1.4 mL 2.8 mL

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Product Datasheets for (RS)-(Tetrazol-5-yl)glycine

Certificate of Analysis / Product Datasheet
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References for (RS)-(Tetrazol-5-yl)glycine

References are publications that support the biological activity of the product.

Arnt et al (1995) Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 285 289 PMID: 8575516

Moroni et al (1995) NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol. 351 371 PMID: 7543185

Schoepp et al (1991) D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 203 237 PMID: 1686860

If you know of a relevant reference for (RS)-(Tetrazol-5-yl)glycine, please let us know.

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Keywords: (RS)-(Tetrazol-5-yl)glycine, (RS)-(Tetrazol-5-yl)glycine supplier, potent, NMDA, receptor, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0312, Tocris Bioscience

Citations for (RS)-(Tetrazol-5-yl)glycine

Citations are publications that use Tocris products.

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Literature in this Area

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