You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Thalidomide 4'-ether-alkylC8-acid
Thalidomide 4'-ether-alkylC8-acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with a terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines for Thalidomide 4'-ether-alkylC8-acid
This product is provided for use in onward chemistry. Suitable solvents can be used.
Technical Data for Thalidomide 4'-ether-alkylC8-acid
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Thalidomide 4'-ether-alkylC8-acid
References for Thalidomide 4'-ether-alkylC8-acid
References are publications that support the biological activity of the product.
If you know of a relevant reference for Thalidomide 4'-ether-alkylC8-acid, please let us know.
Keywords: Thalidomide 4'-ether-alkylC8-acid, Thalidomide 4'-ether-alkylC8-acid supplier, functionalized, PROTACs, cereblon, E3, ubiquitin, ligase, alkyl, C8, linker, conjugate, targeted, protein, degradation, TPD, building, blocks, components, Cereblon, Ligands, Plus, Linkers, 7335, Tocris Bioscience
Citations for Thalidomide 4'-ether-alkylC8-acid
Citations are publications that use Tocris products.
Currently there are no citations for Thalidomide 4'-ether-alkylC8-acid. Do you know of a great paper that uses Thalidomide 4'-ether-alkylC8-acid from Tocris? Please let us know.
Reviews for Thalidomide 4'-ether-alkylC8-acid
There are currently no reviews for this product. Be the first to review Thalidomide 4'-ether-alkylC8-acid and earn rewards!
Have you used Thalidomide 4'-ether-alkylC8-acid?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Targeted Protein Degradation Research Product Guide
This brochure highlights the tools and services available from Bio-Techne to support Targeted Protein Degradation research, including:
- Active Degraders
- TAG Degradation Platform
- Degrader Building Blocks
- Custom Degrader Services
- Ubiquitin-Proteasome System Proteins and Assays
- Assays for Protein Degradation
Targeted Protein Degradation Poster
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia