GPR35 agonist (pEC50 values are 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays respectively). Displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast (Cat. No. 0947).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 342.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||29.21 mL||146.05 mL||292.11 mL|
|0.5 mM||5.84 mL||29.21 mL||58.42 mL|
|1 mM||2.92 mL||14.61 mL||29.21 mL|
|5 mM||0.58 mL||2.92 mL||5.84 mL|
References are publications that support the biological activity of the product.
Neetoo-Isseljee et al (2013) High-throughput identification and characterization of novel, species-selective GPR35 agonists. J.Pharmacol.Exp.Ther. 344 568 PMID: 23262279
If you know of a relevant reference for TC-G 1001, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TC-G 1001, TC-G 1001 supplier, TC-G1001, GPR35, G, protein, coupled, receptor, 35, agonists, selective, 4879, Tocris Bioscience
Citations for TC-G 1001
Citations are publications that use Tocris products.
Currently there are no citations for TC-G 1001. Do you know of a great paper that uses TC-G 1001 from Tocris? Please let us know.
Reviews for TC-G 1001
There are currently no reviews for this product. Be the first to review TC-G 1001 and earn rewards!
Have you used TC-G 1001?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.