Tamoxifen
Biological Activity
Selective estrogen receptor modulator (SERM). Exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Anticancer. Tamoxifen citrate (Cat.No. 0999) is also available.
Technical Data
| M. Wt | 371.51 |
| Formula | C26H29NO |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 10540-29-1 |
| PubChem ID | 2733526 |
| InChI Key | NKANXQFJJICGDU-QPLCGJKRSA-N |
| Smiles | CN(C)CCOC1=CC=C(C=C1)/C(C2=CC=CC=C2)=C(CC)\C3=CC=CC=C3 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 37.15 | 100 | |
| DMSO | 7.43 | 20 |
Preparing Stock Solutions
The following data is based on the product molecular weight 371.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.69 mL | 13.46 mL | 26.92 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
| 10 mM | 0.27 mL | 1.35 mL | 2.69 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.54 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Jordan et al (2003) Tamoxifen: a most unlikely pioneering medicine. Nat.Rev.Drug Discov. 2 203 PMID: 12612646
If you know of a relevant reference for Tamoxifen, please let us know.
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Citations for Tamoxifen
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Pathways for Tamoxifen
