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Biological Activity for Tamoxifen
Tamoxifen is a selective estrogen receptor modulator (SERM). Exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Anticancer. Tamoxifen citrate (Cat.No. 0999) is also available.
Compound Libraries for Tamoxifen
Technical Data for Tamoxifen
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Tamoxifen
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Tamoxifen
The following data is based on the product molecular weight 371.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.69 mL||13.46 mL||26.92 mL|
|5 mM||0.54 mL||2.69 mL||5.38 mL|
|10 mM||0.27 mL||1.35 mL||2.69 mL|
|50 mM||0.05 mL||0.27 mL||0.54 mL|
References for Tamoxifen
References are publications that support the biological activity of the product.
Jordan et al (2003) Tamoxifen: a most unlikely pioneering medicine. Nat.Rev.Drug Discov. 2 203 PMID: 12612646
If you know of a relevant reference for Tamoxifen, please let us know.
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Keywords: Tamoxifen, Tamoxifen supplier, SERM, selective, estrogen, receptor, modulators, antagonists, antagonism, partial, agonists, agonism, anticancer, chemotherapeutic, Estrogen, and, Related, Receptors, 6342, Tocris Bioscience
8 Citations for Tamoxifen
Citations are publications that use Tocris products. Selected citations for Tamoxifen include:
Laurie et al (2020) A homogeneous bioluminescent immunoassay to probe cellular signaling pathway regulation. Commun Biol 3 8 PMID: 31909200
Ya-Jing et al (2023) Metabotropic glutamate receptor 5-mediated inhibition of inward-rectifying K+ channel 4.1 contributes to orofacial ectopic mechanical allodynia following inferior alveolar nerve transection in male mice. J Neurosci Res 101 1170-1187 PMID: 36807930
Paul L et al (2017) Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity. Front Pharmacol 7 503 PMID: 28066250
Ying et al (2012) Daidzein induces neuritogenesis in DRG neuronal cultures. J Biomed Sci 19 80 PMID: 22931352
Silva et al (2019) Study of the Combination of Self-Activating Photodynamic Therapy and Chemotherapy for Cancer Treatment. Biomolecules 9 PMID: 31434290
Susana et al (2020) Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer. Cancer Cell 38 516-533.e9 PMID: 32976773
Rachael et al (2020) ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response. Nat Genet 52 187-197 PMID: 31913353
Alison L et al (2019) Rapid Plasticity of Higher-Order Thalamocortical Inputs during Sensory Learning. Neuron 103 277-291.e4 PMID: 31151774
Do you know of a great paper that uses Tamoxifen from Tocris? Please let us know.
Reviews for Tamoxifen
Average Rating: 5 (Based on 1 Review.)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.