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TM 5275 sodium salt
Biological Activity for TM 5275 sodium salt
TM 5275 sodium salt is a plasminogen activator inhibitor-1 (PAI-1) inhibitor. Orally bioavailable.
Compound Libraries for TM 5275 sodium salt
Technical Data for TM 5275 sodium salt
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for TM 5275 sodium salt
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for TM 5275 sodium salt
The following data is based on the product molecular weight 543.97. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.84 mL||9.19 mL||18.38 mL|
|5 mM||0.37 mL||1.84 mL||3.68 mL|
|10 mM||0.18 mL||0.92 mL||1.84 mL|
|50 mM||0.04 mL||0.18 mL||0.37 mL|
Product Datasheets for TM 5275 sodium salt
References for TM 5275 sodium salt
References are publications that support the biological activity of the product.
Yamaoka et al (2011) Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors. Chem.Pharm.Bull. 59 215 PMID: 21297302
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1 Citation for TM 5275 sodium salt
Citations are publications that use Tocris products. Selected citations for TM 5275 sodium salt include:
Sun-Hee et al (2022) Secretory SERPINE1 Expression Is Increased by Antiplatelet Therapy, Inducing MMP1 Expression and Increasing Colon Cancer Metastasis. Int J Mol Sci 23 PMID: 36076991
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Literature in this Area
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