Taxol Janelia Fluor ® 549

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Description: Yellow fluorescent taxol derivative; probe for microtubule staining
Alternative Names: Taxol-JF549
Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-6-(azetidin-1-yl)-3H-xanthen-9-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate formate
Purity: ≥90% (HPLC)
Protocols (1)
Literature (1)

Biological Activity for Taxol Janelia Fluor ® 549

Taxol Janelia Fluor ® 549 is a yellow fluorescent taxol derivative for imaging of the microtubule cytoskeleton. Protocol available. Excitation maximum = 556 nm; emission maximum = 575 nm.

For more information on how Taxol-Janelia Fluor® 549 may be used, see our protocol.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data for Taxol Janelia Fluor ® 549

Taxol Janelia Fluor <sup>®</sup> 549 Dye Spectra
Emission Color Yellow
λabs 556 nm
λem 575 nm
Application Flow Cytometry, Confocal Microscopy, Super Resolution Microscopy (SRM)

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Technical Data for Taxol Janelia Fluor ® 549

M. Wt 1407.49
Formula C77H76N4O19.HCOOH
Storage Store at -20°C
Purity ≥90% (HPLC)
Smiles O=C(O[C@]12C([C@@H]([C@]3(C(C)(C([C@H](C4=O)OC(C)=O)=C([C@H](C3)OC([C@@H]([C@@H](NC(C5=CC=CC=C5)=O)C6=CC=CC=C6)O)=O)C)C)O)OC(C7=CC=CC=C7)=O)[C@]4([C@H](C[C@H]1OC2)OC([C@@H](NC(C8=CC=C(C([O-])=O)C(C9=C(C(OC%10=C9C=CC(N%11CCC%11)=C%10)=C/%12)C=CC%12=[N+]%13CCC\%13)=C8)=O)C)=O)C)C.[H]C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Taxol Janelia Fluor ® 549

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 14.07 10

Preparing Stock Solutions for Taxol Janelia Fluor ® 549

The following data is based on the product molecular weight 1407.49. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.1 mL 35.52 mL 71.05 mL
0.5 mM 1.42 mL 7.1 mL 14.21 mL
1 mM 0.71 mL 3.55 mL 7.1 mL
5 mM 0.14 mL 0.71 mL 1.42 mL

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Product Datasheets for Taxol Janelia Fluor ® 549

References for Taxol Janelia Fluor ® 549

References are publications that support the biological activity of the product.

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Citations for Taxol Janelia Fluor ® 549

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Protocols for Taxol Janelia Fluor ® 549

The following protocol features additional information for the use of Taxol Janelia Fluor ® 549 (Cat. No. 6267).

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

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