Taxol Janelia Fluor ® 549

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Cat.No. 6267 - Taxol Janelia Fluor 549 | C77H76N4O19.HCOOH
Description: Yellow fluorescent taxol derivative; probe for microtubule staining
Alternative Names: Taxol-JF549
Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-6-(azetidin-1-yl)-3H-xanthen-9-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate formate
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Protocols (1)
Literature (1)

Biological Activity

Yellow fluorescent taxol derivative for imaging of the microtubule cytoskeleton. Protocol available. Excitation maximum = 556 nm; emission maximum = 575 nm.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data for Taxol Janelia Fluor ® 549

Emission Color Yellow
Brightness
λabs 556 nm
λem 575 nm
Application Flow cytometry, confocal microscopy, super resolution microscopy SRM

Technical Data

M. Wt 1407.49
Formula C77H76N4O19.HCOOH
Storage Store at -20°C
Purity ≥98% (HPLC)
InChI Key ZEBDFYUXCMYUMD-FZIPNWKRSA-N
Smiles O=C(O[C@]12C([C@@H]([C@]3(C(C)(C([C@H](C4=O)OC(C)=O)=C([C@H](C3)OC([C@@H]([C@@H](NC(C5=CC=CC=C5)=O)C6=CC=CC=C6)O)=O)C)C)O)OC(C7=CC=CC=C7)=O)[C@]4([C@H](C[C@H]1OC2)OC([C@@H](NC(C8=CC=C(C([O-])=O)C(C9=C(C(OC%10=C9C=CC(N%11CCC%11)=C%10)=C/%12)C=CC%12=[N+]%13CCC\%13)=C8)=O)C)=O)C)C.[H]C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 14.07 10

Preparing Stock Solutions

The following data is based on the product molecular weight 1407.49. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.1 mL 35.52 mL 71.05 mL
0.5 mM 1.42 mL 7.1 mL 14.21 mL
1 mM 0.71 mL 3.55 mL 7.1 mL
5 mM 0.14 mL 0.71 mL 1.42 mL

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References

References are publications that support the biological activity of the product.

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Citations for Taxol Janelia Fluor ® 549

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Protocols for Taxol Janelia Fluor ® 549

The following protocol features additional information for the use of Taxol Janelia Fluor ® 549 (Cat. No. 6267).

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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