MRS 4062 triethylammonium salt

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Cat.No. 4261 - MRS 4062 triethylammonium salt | C18H26N3O15P3.4(C2H5)3N | CAS No. 1309871-50-8
Description: Selective P2Y4 receptor agonist
Chemical Name: N4-Phenylpropoxycytidine-5'-O-triphosphate tetra(triethylammonium) salt
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

Selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).

Technical Data

M. Wt 1022.09
Formula C18H26N3O15P3.4(C2H5)3N
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 1309871-50-8
PubChem ID 90488925
InChI Key ZCDZFMKRHPANNI-IHQKQWLFSA-N
Smiles O[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N3C(N/C(C=C3)=N\OCCCC2=CC=CC=C2)=O)[C@@H]1O.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water (supplied pre-dissolved at a concentration of 10mM)

Preparing Stock Solutions

The following data is based on the product molecular weight 1022.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.98 mL 4.89 mL 9.78 mL
5 mM 0.2 mL 0.98 mL 1.96 mL
10 mM 0.1 mL 0.49 mL 0.98 mL
50 mM 0.02 mL 0.1 mL 0.2 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Maruoka et al (2011) Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphate δ-ester modifications as selective agonists of the P2Y4 receptor. J.Med.Chem. 54 4018 PMID: 21528910


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Keywords: MRS4062 triethylammonium salt Selective P2Y4 agonists Receptors Purinergic purinoceptors Purinergic P2Y Receptors

1 Citation for MRS 4062 triethylammonium salt

Citations are publications that use Tocris products. Selected citations for MRS 4062 triethylammonium salt include:

Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730


Do you know of a great paper that uses MRS 4062 triethylammonium salt from Tocris? If so please let us know.

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