Potent and selective PI 4-K IIIβ inhibitor (IC50 = 54 nM). Exhibits >1,800-fold selectivity for PI 4-K IIIβ over PI 4-K IIIα and PI 4-K IIα, respectively. Exhibits antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 450.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||11.09 mL||55.44 mL||110.88 mL|
|1 mM||2.22 mL||11.09 mL||22.18 mL|
|2 mM||1.11 mL||5.54 mL||11.09 mL|
|10 mM||0.22 mL||1.11 mL||2.22 mL|
References are publications that support the biological activity of the product.
Mejdrová et al (2015) Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action. J.Med.Chem. 58 3767 PMID: 25897704
If you know of a relevant reference for MI 14, please let us know.
View Related Products by Product Action
Keywords: MI 14, MI 14 supplier, MI14, antivirals, phostphatidylinositol, 4, kinases, inhibitors, inhibits, IIIbeta, PI4-Kinase, RNA, viruses, potent, selective, Other, Kinases, Antivirals, 5604, Tocris Bioscience
Citations for MI 14
Citations are publications that use Tocris products.
Currently there are no citations for MI 14. Do you know of a great paper that uses MI 14 from Tocris? Please let us know.
Reviews for MI 14
There are currently no reviews for this product. Be the first to review MI 14 and earn rewards!
Have you used MI 14?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.