Muscarinic acetylcholine receptor agonist; mimics the activity of acetylcholine.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 301.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.32 mL||16.6 mL||33.2 mL|
|5 mM||0.66 mL||3.32 mL||6.64 mL|
|10 mM||0.33 mL||1.66 mL||3.32 mL|
|50 mM||0.07 mL||0.33 mL||0.66 mL|
References are publications that support the biological activity of the product.
Jin (2003) Muscarine, imidazole, oxazole and thiazole alkaloids. Nat.Prod.Rep. 20 584 PMID: 14700201
Boukouvalas et al (2007) A concise asymmetric synthesis of (+)-muscarine from (S)-γ-hydroxymethyl-γ-butyrolactone. Tetrahedron Lett. 48 2971
If you know of a relevant reference for (+)-Muscarine iodide, please let us know.
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Keywords: (+)-Muscarine iodide, (+)-Muscarine iodide supplier, (+)-Muscarine, iodide, muscarinics, acetylcholine, ach, receptors, machrs, agonists, mimetic, Non-selective, Muscarinics, 3074, Tocris Bioscience
2 Citations for (+)-Muscarine iodide
Citations are publications that use Tocris products. Selected citations for (+)-Muscarine iodide include:
Dumalska et al (2008) Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. J Neurosci 28 8003 PMID: 18685025
Liu et al (2016) Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice. J Neurosci 36 957 PMID: 26791223
Do you know of a great paper that uses (+)-Muscarine iodide from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.