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(+)-Muscarine iodide is a muscarinic acetylcholine receptor agonist; mimics the activity of acetylcholine.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 301.17. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.32 mL||16.6 mL||33.2 mL|
|5 mM||0.66 mL||3.32 mL||6.64 mL|
|10 mM||0.33 mL||1.66 mL||3.32 mL|
|50 mM||0.07 mL||0.33 mL||0.66 mL|
References are publications that support the biological activity of the product.
Jin (2003) Muscarine, imidazole, oxazole and thiazole alkaloids. Nat.Prod.Rep. 20 584 PMID: 14700201
Boukouvalas et al (2007) A concise asymmetric synthesis of (+)-muscarine from (S)-γ-hydroxymethyl-γ-butyrolactone. Tetrahedron Lett. 48 2971
If you know of a relevant reference for (+)-Muscarine iodide, please let us know.
Keywords: (+)-Muscarine iodide, (+)-Muscarine iodide supplier, (+)-Muscarine, iodide, muscarinics, acetylcholine, ach, receptors, machrs, agonists, mimetic, Non-selective, Muscarinics, 3074, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for (+)-Muscarine iodide include:
Liu et al (2016) Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice. J Neurosci 36 957 PMID: 26791223
Dumalska et al (2008) Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. J Neurosci 28 8003 PMID: 18685025
Do you know of a great paper that uses (+)-Muscarine iodide from Tocris? Please let us know.
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
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