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Antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||5.23||25 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 209.25. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||19.12 mL||95.58 mL||191.16 mL|
|1.25 mM||3.82 mL||19.12 mL||38.23 mL|
|2.5 mM||1.91 mL||9.56 mL||19.12 mL|
|12.5 mM||0.38 mL||1.91 mL||3.82 mL|
References are publications that support the biological activity of the product.
Lachgar et al (1998) Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 138 407 PMID: 9580790
Meisheri et al (1993) Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 45 271 PMID: 8435087
Tsoporis et al (1993) Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 11 1337 PMID: 8133016
Merck Index 12 6290
If you know of a relevant reference for Minoxidil, please let us know.
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Keywords: Minoxidil, Minoxidil supplier, K+, channel, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, antihypertensive, activators, Kir6, rectifier, 0583, Tocris Bioscience
1 Citation for Minoxidil
Citations are publications that use Tocris products. Selected citations for Minoxidil include:
Sun et al (2014) Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel. Sci Rep 4 4934 PMID: 24816792
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Literature in this Area
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